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Anemia
Is there anything you can do to help the Anemia? When I started treatment my Hemaglobin went down to low so I am on the Pegasys (Ignore spelling) Victruelis and Ribavarin now they have me on the Rib 3 in the morning and thats it the Victrulis 3 times a day. This week I dropped down to 9.7 I think was my number with out going back to look I was at 10.2 so If I keep dropping I am afraid of what may happen I have come this far! If I should eat something or take something I will! I dont understand why I go back and fourth so much. I see her Monday so if there is more pressing questions from someone else no need to respond I am actually not feeling to bad right now was tired earlier every day is a new emotion or question one day I will answer everyone's questions just like you guys!
Best Answer
Your like a encylopedia treat I will I just wrote it down on my sheet for her!
Thank you!
Thank you!
Thank you so much and your right its not low now I am hoping it doesnt do it again this stuff sure makes you worry! I guess its because you come so far you don't want anything to wreck your goal.
No, but rest. Do your CBC's once a week to watch it. Its not that low. I stayed around 9 and my doctor still felt that was ok but if it dropped below 9 she would get concerned. It never did but I sure felt it. You will see lots of folks on here to went low without helper drugs but its btwn you and the doctor. Good luck and don't get to worried about it, sounds like your in good hands.
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Anemia developed among recipients of both PIs. Hemoglobin decreases below 10 g/dL (grade 2 toxicity) occurred in 49% of patients who received a BOC regimen compared to 29% of those who received the SOC regimen, whereas 9% had a hemoglobin decline of <8.5 g/dL (grade 3 toxicity).12 Among patients treated with T12PR, hemoglobin levels of <10 g/dL were observed in 36% of patients compared to in 14% of patients who received SOC, and 9% had hemoglobin decreases to <8.5 g/dL.16 Because hematopoietic growth factors were not permitted during the TVR trials, there was a 5%-6% higher rate of treatment discontinuation among
those who developed anemia than among those who did not. However, neither anemia nor RBV dose reduction adversely affected the SVR rate. Of note is that in the BOC trial, SVR rates in patients managed by RBV dose reduction alone were comparable to those in patients managed with erythropoietin therapy.23 Similarly, in the TVR trials, dose reduction of RBV had no effect on SVR rates, and therefore dose reduction should be the initial response to management of anemia.24 Because the duration of BOC therapy (24 to 44 weeks) is longer than the duration of TVR therapy (12 weeks), the frequency of anemia is likely to be greater in BOC-containing regimens, leading to more RBV dose reductions and consideration of erythropoietin use. However, the potential benefits of erythropoietin must be weighed against its potential side effects, the fact that its use in HCV therapy is not approved by the FDA, and its considerable cost. If a PI treatment–limiting adverse event occurs, PegIFN and RBV can be continued provided that an on-treatment response had occurred. There are no data to help guide substitution of one for the other
HCV PI. If a patient has a serious adverse reaction related to PegIFN and/or RBV, the PegIFN and/or RBV dose should be reduced or discontinued. If either PegIFN and/or RBV are discontinued, the HCV PI
should be stopped.
https://www.aasld.org/practiceguidelines/Documents/2011UpdateGenotype1HCVbyAASLD24641.pdf