Aa
MedHelp.org will cease operations on May 31, 2024. It has been our pleasure to join you on your health journey for the past 30 years. For more info, click here.
Aa
A
A
A
Close
Avatar universal

Sofosbuvir/Ribavirin Side Effects

I am waiting for the SOF/RIBA combo therapy to be available and have not been able to find much info on the side effects experienced by those who have done the 12 week treatment. Most of what I find about RIBA sides has to do with it in combination with peginterferon. Anyone out there who has done this combo in trials who could share their experience?

Thanks!
Best Answer
Avatar universal
Hi,
They are still collecting data on the effects but according to the posts here there are few if any side effects for a person who is relatively healthy apary from having HCV.
I experienced some digestive upsets,insomnia and headaches, irritability, and a bit of a rash but most of my real discomfort was a result of extra hepatic manifestations due to HCV and cirrhosis.
Most people feel irritable on the ribavirin but again the degree of 'riba rage' depends on the individual. My Dr. told me that almost all the people in my study complained of some side effects but that overall (nationwide) the reports were that sx were minimal.
Of course compared to SOC, it is a cakewalk.
All the best :)
25 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Has your labwork shown that you are undetected for the virus? My husband lasted only 5 weeks on triple treatment (with Incivik) because he became severely anemic and needed numerous blood transfusions.

Lucky for him he remained undetected for 8 months until he got his transplant. So he doesn't regret having done it despite the very hard time he had with it.

You may want to try the new treatments when available to you. I hear the side effects are not nearly as bad as the triple treatment.

Best of luck
Nan
Helpful - 0
Avatar universal
HI. I also caught this disease when I was very young in the late 60s early 79s
. I was married to an iv drug user.  The experts say I probably didnt catch it by sexual contact but probably by using his razor/toothbrush. I was diagnosed last year with f4 fibrosis but not cirrhosis genotype 1a. Started triple therapy 10 weeks ago stopped on Monday as couldn't cope with side effects.  The physical side effects I could cope with but nit the daily panic attacks I was getting. Specialist advised me to stop coz I was so.I'll.  Still ggetting the panic attacks.  Am waiting for the new treatment to come to the UK.  Feel like I'm going crazy. I am a 65 year old female. HELP
Helpful - 0
Avatar universal
I am supposed to start this drug in February. I am woprried abut side effects but sound a lot better than the alternative which is to die...I am not eligible for a liver transplant and was not eligible for interferon due to other problems not related to Hep C.  I wish you luck.  Anyone from the Sacramento, CA?  If use the support and have not found one in this area, although have talked to  a lot of people educating them abut the need to be careful and anyone that is a baby boomer  should get treatment or at least a test to see if they have the disease.  As in my case I got it through sex when I was 19/  This is supposed to be relatively rare in the scope of things.  I am proof that it is not just needles users as well.  Ede23
Helpful - 0
142526 tn?1397090672
Hi mcmaklin,  go to "post a question" and start a new post with your questions. This will help others see your questions and someone may be able to help with answers.
Helpful - 0
Avatar universal
Hi, please tell me, I am genotype 1, don't know if a or b, living in Poland. How's happened that you have access to such Inteferon free treatment? If clinical trials where? And how long you had to wait?
Helpful - 0
Avatar universal
  Hi Hector, one question I have been wondering about for a while;  I remember my Dr( Diana Sylvestre) mentioning that for Geno 1a's, that they will STILL be using Interferon, (and Riba) with Sofosbuvir, although geno 2's will do a regimen that you are currently on (Interferon Free)~
    Since you and my Hubs are both on Interferon Free regimens, and both geno 1's, what stats are they using,  which would lead them to believe Interferon is even needed?
Helpful - 0

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.