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Sofosbuvir/Ribavirin Side Effects

I am waiting for the SOF/RIBA combo therapy to be available and have not been able to find much info on the side effects experienced by those who have done the 12 week treatment. Most of what I find about RIBA sides has to do with it in combination with peginterferon. Anyone out there who has done this combo in trials who could share their experience?

Thanks!
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Avatar universal
Hi,
They are still collecting data on the effects but according to the posts here there are few if any side effects for a person who is relatively healthy apary from having HCV.
I experienced some digestive upsets,insomnia and headaches, irritability, and a bit of a rash but most of my real discomfort was a result of extra hepatic manifestations due to HCV and cirrhosis.
Most people feel irritable on the ribavirin but again the degree of 'riba rage' depends on the individual. My Dr. told me that almost all the people in my study complained of some side effects but that overall (nationwide) the reports were that sx were minimal.
Of course compared to SOC, it is a cakewalk.
All the best :)
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