I've been very interested in new meds. I think the PIs coming next year will rule for only a few years. Vertex knows this and is working on the second generation of PI. I love this link about all the meds in the pipeline and their status.
http://www.hcvdrugs.com/
All the pharmaceutical companies are working on the next generation already. They also know that the initial wave of sales from the first PI available will be huge.