I too had read something along these lines and you have bought it back to my very weary mind. thanks for the good word, jerry
Riba reduction in RVR patients post week 16 does not prejudice SVR.
There was a good study on this but I didn't bookmark it.(Don't bookmark anything now).
Role of riba critial in first 16 weeks to supress design of successful variant.
I would be surprised and disappointed if you don't clear.
The half life is not really an issue.
I was able to achieve undetectable with a dose as low as 200 mg. of ribavirin + ifn. Riba caused severe gastrointestinal problems for me along with anemia. That was over the course of many years of treatments. Unfortunately I've always had rebound. Never got an SVR. I am amazed you made it this far with such a high dose. I don't recommend you go that low however.
Yeah, I tried reducing, first to 1000mg, then 800, then 600, no luck. No riba yesterday but still picked up a headache last nite. The migraines were my main concern when deciding treatment. I feel fortunate to have made it as long as I did with out them becoming chronic. Any reason you can think of for me not not to continue on with the Peg/Alinia? (asuming the migraines back off) jerry
If you werent taking Alinia, you would be risking breakthru and/or Relapse.
So you would be better off dose reducing to 600 and see if that helps.
As you are taking Alinia who knows.
And as you well and truely RVRed then 24 weeks may well have been enough.
You are taking a risk, but in my opinion not a very big one.
The riba half life is 12 days.
CS
283,000vl. Yes, my hope also. I plan on continuing the Peg/Alinia for the additional 12 weeks at least. jerry