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Avatar universal

alcohol and interferon

So, why can't you drink if youre going through treatment? Does it make you sick? Or is it because youre doing damage to your liver

Yesterday I didn't drink enough water. I had a few beers, though its frown upon, and I woke up today with a fever a feeling really sick. I slept until 3 or 4 in the afternoon. Everything was sore and achey...

Feedback please
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475300 tn?1312423126
First of all you are treating to get rid of a virus that will kill your liver.

Second of all alcohol will speed up the death of your liver

Third of all if your doc knew that you were going to drink he / she probably would not treat you.

fourth of all most if not all the people on this forum want to get well & LIVE

fifth of all if you need a liver transplant and drink, you will not get one and die

Those are the cold hard facts as I see it,    

GSDgirl
Helpful - 0
320078 tn?1278344720
if you treating your liver it is already damaged.  alcohol will only increase the damage and the speed of the diases.  if you are serious about your treatment, you need to stop drinking!
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446474 tn?1446347682
"Why can't you drink if youre going through treatment?"
It gets to be kinda hard injecting yourself with one hand and while having a beer in the other!..

Seriously, If you don't understand why you shouldn't drink at this point you probably shouldn't be starting treatment. Doing treatment is no easy task. It requires commitment and responsibility for up to and sometimes beyond a year of your life. If "I had a few beers... slept until 3 or 4 in the afternoon" is a common occurrence for you doing therapy SUCCESSFULLY is going to cause you to have to modify your lifestyle in a dramatic and fundamental way.
Of course the decision is up to you.

I wish you all the best decide.
Hector
Helpful - 0
Avatar universal
Alcohol is about the worst thing you can expose yourself to while having HCV.  Overdosing on some drugs may be worse but few people will do it day in and day out as they do with alcohol.  Many drinkers just keep throwing fuel on the fire.

It's fine if you want to do it but...... you are probably wasting your time treating.  You should either do just one or the other.

alcohol consumption increases viral load
"             "               increases liver damage
"             "              decreases the success rate of treatment
History of alcool consumption = no chance at a transplant
Agreed; if you tell your doctor you will likely get jerked off treatment.  That might be a good thing since the odds of success are slim if drink through TX.

Sorry; not much good to say about drinking while on TX or drinking with HCV.  Go check out what end stage liver disease looks like; it's even less fun than TX.

There are many threads in this forum about the subject.  Use the search engine and type in alcohol, HCV.  This topic has come up many many times.

Good luck and I'm sorry if I came on strong.  I hope you can stop drinking.  Most of us genotype 1's only have about a 45% of clearing when we do everything right.  To increase your chances of clearing I'd stop drinking.

best,
willy
Helpful - 0
Avatar universal
Ignore the alcohol nazis.
The reason way you should'nt drink alcohol has nothing to do with throwing fuel on the fire or causing more liver damage. Although they good reasons.
Alcohol and IFN hate each other. Alcohol stops IFN from working.
Your liver has to rid itself of the alcohol before the IFN induced immune response can occur again. IFN is metabolised in your Liver.

CS
Helpful - 0
Avatar universal
Should add 1 more thing. If you are stage 3 or above and you drink even occasionally this would not be wise. Below stage 3 the occasional drink will probably not do you any harm. But not on Tx.
CS

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Avatar universal
Achtung!!!

CS...... I'm not sure what criteria it takes to be considered an "alcohol Nazi"

Near as I can see people were laying out basic (and unhappy) truths about alcohol as it pertains to TX and HCV.  Those truths may be unpleasant for one who is drinking.  They are decidely less unpleasant than the alternative result or outcomes of 1) drinking while one has HCV or 2) attempting to drink alcohol while on treatment. (IMHO)

I suspect that Joel asked the question already partially knowing the answer.  The folks who took time out to give him an answer to his question don't deserve your judgement or labeling.  I saw no judgement in my or the other posts; I did see people trying to dissuade him from the practice of drinking while on TX through providing him the reasons.  It sounds as if his liver and general well being also weighed in on the subject the day after.  : )

I'm not sure which is the cruelest; to try to deter people from drinking or to offer somesome kind of "well, a little might not hurt" sort of reply that could serve as a means of enabling a practice that is neither good for the liver or for treatment.  

Best,
Willy

Helpful - 0
Avatar universal
While I wasn’t that opposed to what you had to say some of what you said is not backed up by evidence.
Willy- Alcohol is about the worst thing you can expose yourself to while having HCV
---------------------------------------
Not true. Heavy alcohol consumption is.
Whether anyone likes to admit it or not there is a safe alcohol consumption limit.
What that limit is may be debateable, but there will be an amount that we all can drink that does not progress or further liver damage.
To make a blanket statement that any and all alcohol consumption = cirrhosis is simply misleading.
I will admit that zero alcohol is a safe limit but so is 1 or 2 drinks a month for someone who is F2 or less.

I'm not sure which is the cruelest; to try to deter people from drinking or to offer somesome kind of "well, a little might not hurt" sort of reply that could serve as a means of enabling a practice that is neither good for the liver or for treatment.  

A little doesn’t hurt full stop. The only question is how much is a little.
It is easier to say no alcohol with HCV but that doesn’t make it true.
Where is the evidence.

Joel asked -So, why can't you drink if youre going through treatment? Does it make you sick? Or is it because youre doing damage to your liver”

The reason you should not drink on Tx is because it reduces your SVR odds and by quite a lot. Its not because it damages your liver but because it slows down Interferon absorption.
See your liver as Male. It sequentially multitasks and has to process the alcohol before it goes back to processing the IFN.

Saying anything else is conjecture.
CS
Helpful - 0
Avatar universal
I think you both make very good points from different angles.  Allows for a broader perspective and you both put in good info that allows for people to weigh it out and decide what makes sense to them.  Thanks to both of you.

Trish
Helpful - 0
Avatar universal
Glad to provide others recommendations;

http://pubs.niaaa.nih.gov/publications/arh27-3/232-239.htm

http://www.webmd.com/content/article/4/1680_51403

http://www.janis7hepc.com/faq_page_five.htm

http://www.hepctrust.org.uk/Wellness/caring-for-yourself/

http://www.phac-aspc.gc.ca/hepc/pubs/nc-hcp-sn-is/practice_e.html

Alcohol is the most commonly abused toxic substances that heppers should avoid.  I'm speaking generally and you are splitting infinitives.  I don't see any professionals quantifying use of alcohol.  You seem to feel comfortable suggesting that there is a range which is safe.  

Recommending people don't drink alcohol if they have HCV or are on treatment is well established, documented, and a very popular opinion of medical professionals; not only  "alcohol Nazis".   My opinion..... but since people don't reliably report how many drinks they actually consume (especially over the years) the data is often imprecise.  People don't always progress at the same rate for a variety of reasons;  daily dosage, age, sex, weight, genetics, other co-factors (use of pot, diet), etc.

It is difficult to recommend an acceptable amount since it will vary from person to person.  I think the reason you see the tendency for professionals simply nix any use.  It's one thing they know that's safe.  I'm inclined to do the same as the professionals.  It's hardly an uncommon reply; rather it's nearly the rule.  I've provided a few links which support my reply.  

To round out the data we supply people who ask such questions it would be great to see some links which supply the "allowable number" of drinks we can imbibe.  That would be useful for the next person who asks at MedHelp.  ; )  I personally feel that it's a slippery slope to suggest an allowable range when we (generally speaking) are not doctors, may not have any medical credentials, or specific medical information about the person asking the question.  I feel that it's safer to err towards avoidance of alcohol.  It's just my opinion.

I was aware of the connection with diminished response and SVR rates for those who drink but hadn't been aware that alcohol "stops interferon from working".  I'd love to have data/ links on that since it bears so directly on this thread and many others like it in this forum.  

Best,
Willy
Helpful - 0
Avatar universal
I have posted again because i didnt like the formatting. Oh for an edit function

Willy
From HepatitisAustralia
http://www.hepatitisaustralia.com/about_hepatitis/drugs.html

Should I cut down on alcohol?
There is no evidence to suggest that total abstinence from alcohol is necessary when you have hepatitis C, unless you have cirrhosis. However, it is recommended that people with hepatitis C who consume alcohol in large quantities should reduce the amount they drink, as alcohol does increase the rate of liver damage.

SonicBandaid Post
http://www.medhelp.org/forums/hepatitis/messages/46836.html

What nonsense!  Sure, its BETTER if you aren't drinking and I certainly advise my patients not to drink more than 7 standard drinks per week (in fact, alcohol consumption at that level or lower is a prerequisite for funding therapy in Aus), but there is little evidence to suggest low level social alcohol consumption of this sort impairs your response to treatment in any measurable way or accelerates your liver disease (assuming you don't have an alcohol PROBLEM or alcohol related liver disease to start with. We are supposed to practice "evidence based medicine" and I would LOVE to see any evidence that getting people to be completely abstinent for 6 months prior to treating HCV with IFN/Riba makes any difference to outcome (other than the fact you unnecessarily delay therapy)

It is also not realistic. If I insisted on this, I'd wind up treating about 25% of the patients I have. The Puritans have a LOT to answer for.  Several patients I currently treat also tell me that 1-2 glasses of wine (on the nights they inject, only) actually makes the side effects more tolerable.
Cheers,
Sonic

Note: SonicBandaid is a Doctor who has practiced in the US and now lives in Aust.
Or at least did last year.

How much more do you want.
I would like some studies that back up the no alcohol claim and there aint too many of them.

Wanna play study wars
CS


Helpful - 0
476246 tn?1418870914
I personally don't think it's a good idea to drink when you have a liver illness. But that is my personal point of view, nothing to do with studies. But then again, since I don't drink alcohol (since 1998), I might have my own preconceived ideas. :-)

I have a little story though. My step mom has hep c. Dx in the 90ies. She contracted it through a blood transfusion in 87. Anyway, she has had many biopsies, each time it is A1 F1. She does not want to treat. Being French, she has her little glass of red wine every day and might have some kind of aperitif in the evening. The results of her biopsy haven't budged in years and she is 70 now. She's had all kinds of other operations and chemotherapy due to breast cancer, tumors in the stomach...

I don't know what to think....

Marcia
Helpful - 0
Avatar universal
CS; I don't know this web site you provided ....who they are, if they have medical credentials etc, but the very first thing they say is;

http://www.hepatitisaustralia.com/about_hepatitis/drugs.html

"There is a higher risk of developing liver disease, including cirrhosis, if you have hepatitis C and drink alcohol. Alcohol is also likely to affect your response to treatment, making treatment less effective."

The first one that I provided was;
http://pubs.niaaa.nih.gov/publications/arh27-3/232-239.htm

"Patients infected with the hepatitis C virus (HCV) who drink heavily are likely to suffer more severe liver injury, promoting disease progression to cirrhosis and increasing their risk for liver cancer. Some research, although not conclusive, suggests that even moderate drinking may spur liver damage in HCV–infected patients".

Dr  Schiff is one of this nations leading hepatologists.  This link comes from a branch of the NIH.  I consider both good sources of information.

No point in quibbling over whether you can drink.  I provided information which suggested it was a bad idea.  I backed it up with solid references.  If you want to provide advice to people that they can drink and drink safely while having HCV or on TX (such as with Sonics post) ...then by all means .....go for it.  Post it.  : )

I look forward to seeing your future posts on the subject.

best,
Willy
Helpful - 0
Avatar universal
I don't think your step mom is an isolated case.  There are many people who drink moderately or even heavily to do not progress in an extreme or even in a moderate fashion.  Sadly, the reverse is also true.  For reasons not well understood some people who do not use drugs or alcohol progress to stage 4 rapidly.  (I lost a friend a few years ago; stage 4 in her mid 40's)  The progression of damage is not well understood but it is clear that alcohol does indeed play a part in disease progression.  What we can't know is how it will play out in any one individual.

I hope that there will come a time that we all get cured and the issue is less thorny.

best,
Willy
Helpful - 0
476246 tn?1418870914
I guess one can never know before hand how one is going to react. Better safe than sorry. I am definitely staying away from it, and so is my daughter (by my suggestion and her own choice) since she was dxed a few weeks ago.

Best,

Marcia
Helpful - 0
179856 tn?1333547362
considering most of us are taught that excessive alcohol intake will lead to cirhhosis even if you don't have hep C...I think the subject is just so stupid it's beyond any imagination.  Personally if you want to drink don't bother doing treatment since it's been proven that it CAN DEFINITELY effect interferon and take away all it's potency.

The reasons you SHOULD drink on treatment:

I want treatment to fail treatment so I'll drink and take away all efficacy of the meds! YAY!

I want to die in End Stage Liver Disease, even though I could have prevented it - those Pabst Blue Ribbons were just too tempting to make it worth it! YAY!

I want to show everyone just how weak I am and that I don't give a whit about their lives or pain either! MORE YAY!

Just my personal opinion but I'm tired to DEATH of this stupid question.  It's nothing different than someone with lung cancer asking ok if it's ok to cut down to 2 packs of Lucky's a day from 4. I mean how much COMMON SENSE do people need to have to realize the OBVIOUS?
Helpful - 0
Avatar universal
My doctor said no alcohol, that would just sabotage your treatment.

I don't need to know the technical reasons, its doctor's orders.  I'm not a child or an idiot and I'm not about to trash 48 weeks of treatment hell just because I haven't heard a convincing reason not to introduce poison into my system.  I'm an adult, paying for the best professional care and advice available.  

Its doctors orders, not open for debate.  NO ALCOHOL
Helpful - 0
Avatar universal
I know you've noticed as you have been with us a long time but it ceases to amaze me how common sense can elude people if they are trying to justify bad behavior.  As you and jd stated you have to be a @#$&+*%  IDIOT to think you can drink while on tx.  I'll never drink again whether I SVR or not because my liver was pretty well shot to begin with.  Yeah, drink if you want to, just don't make any long term plans because you won't be around to fulfill them.
Trinity
Helpful - 0
179856 tn?1333547362
Especially when you're saying things like I didn't drink enough water but then I had a bunch a beers and all of a sudden I feel sick and feverish and sore and achey but why why why????? LOL I tend to think these posts can't be real because nobody on earth could really be THAT stupid.  You know what i Mean?

Shoot if I put a needle in my eye and it hurts like hell I won't be posting the next day help I put a needle in my eye I can't believe it but it hurt why did it hurt like that?

hahahahaha.

(I'm glad that YOU get it.........after all we can only worry about the people who do...the others aren't going to be around to bug us that long - after 3+ years on this forum, it's pretty easy to tell who is serious and who is not and I just don't have the patience for the "I want to drink and only do 12 weeks of treatment what are my chances?" people.

Common sense is a MUCh more rare thing than I EVER thought it really was!

(Hey you aren't Trinity because of the Matrix are you? A friend of mine met Keanu Reeves two weeks ago and just told me and it made me think of you and wonder...of course..I keep forgetting to ask you!)
Helpful - 0
476246 tn?1418870914
I love you two! I had totally forgotten how this thread started. Just went and read the first post again. Sometimes I wonder if things are posted for real or if it is just someone trying to stir things up. Or maybe the person is just too young to understand. Mind you, my 18 year old daughter understands that since she has been dxed, it is not cool to have a glass of wine for dinner or a beer with her friends anymore. (we live in Denmark where it is legal to buy alcohol from the age of 16)

Marcia
Helpful - 0
179856 tn?1333547362
Wow you just answered such a big question for me! Now I know why my 17 year old thinks it's ok for him to have a can of beer in the house with his friends now and again.........he thinks he's from Denmark! I KNEW there had to be logic in there somewhere!!!!!!!!!!!!!!!!!!!!!   :)

it's amazing to think that anyone would want to come in an post garbage just to post garbage but it happens all the time. Especially in the summer months and on vacation from school days. Yowza it can get bad - and hard to ignore the little twirps when it happens.

Can you imagine going over to a cancer website and saying half the things we get here? Like hey I have lung cancer and smoke Marlboro's but I want to know if smoking Newports is better for me now?

OK yeah..............  ;)
Helpful - 0
476246 tn?1418870914
You got me cracking up, big time. Thanks!


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Avatar universal
Yes, I took my name from the Matrix.  I think Carrie Anne-Moss is gorgeous for one thing and who wouldn't want to be in love with Neo.  Keanu Reeves is HOT!!  Also, she  was a fighter and a major player until the end and I always admired her tenacity.  So I figured if I was going to have to fight the biggest battle of my life might as well emulate Trinity.  You made me laugh out loud and my co-workers looked at me like was having a melt down or something.  I couldn't stop laughing.  You're really funny and sure enough just when I need a good theraputic laugh it rolls out on this forum.  You're the best!!!
Trinity
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Avatar universal
Read what the Dr said
Sure, its BETTER if you aren't drinking and I certainly advise my patients not to drink more than 7 standard drinks per week

but there is little evidence to suggest low level social alcohol consumption of this sort impairs your response to treatment in any measurable way or accelerates your liver disease (assuming you don't have an alcohol PROBLEM or alcohol related liver disease to start with.

Now I am staying out of this as the guy who started the thead hasnt made another Post.
There is no point thowing statements back at each other.

nygirl7
Your statements on alcohol arent backed backed by evidence. Just Puritantical nonsense. Of cause its better not to drink but you are drawing a long bow saying all and any alcohol causes problems. Find a study that states 10g or less of alcohol is a problem. There are heaps that say >40g is a problem.

Willy
HepatitisAustralia is a reputable site and while not exacltly Medical does have acces to Medical knowledge. If the evidence in Aust or anywhere in the world supported no alcohol they would change what they say.

I would like to know whether his patients having a wine or 2 on shot night svr-ed.
Thats taking a risk.
CS



CS
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