Aa
allergy medicine
i'm curious if it is ok to use flonase. also, is benadryl ok to use. I just finished using my netti pot for nasal allergies. I'm trying to be careful about drug interaction; I haven't started the boc yet.
my study nurse said benadryl was fine for me and i'm in a clinical trial. i have 1/2 at bedtime. btw it's very hard to find tablets. so i got the generic brand at target and brought it to my nurse. she said it had the same ingredients. so i've been using it. it works great for me. take care. belle
I have had good luck with Benedryl (diphenhydramine) I am not crazy how sleepy and thirsty it makes me but just about all antihistamines have anticholinergic side effects. Sure, ask your doctor about it but my guess is that it will be OK. If it works for you now then I would definitely take it. It helps to have as many knows as possible when you are taking new meds & new rescue meds.
Be double sure you drink lots of liquids when you take any antihistamine while treating (well, all the time actually). They can really dry you at as it is and I noticed I was urinating less frequently when I took Allegra (Fexofenadine) during the day and the Benedryl at night. I had to make a conscious effort to drink water almost all the time.
Be double sure you drink lots of liquids when you take any antihistamine while treating (well, all the time actually). They can really dry you at as it is and I noticed I was urinating less frequently when I took Allegra (Fexofenadine) during the day and the Benedryl at night. I had to make a conscious effort to drink water almost all the time.
Thanx for the input. I think I'll stay away from the Flonase for now. I'll research the Benadryl some more.
Benedryl is fine. At least that is what my case manager and my pharmacist said. In addition, when I received my first box of meds from the pharmacy, they included a bottle of Benadryl capsules.
I would check with the pharmacist at the pharmacy that is supplying the Hep C medication. They should have a list of all of your meds. Even if they do not have a list, they should be able to tell you if Flonase is okay to use with Hep C meds.
I would also check with your doctor. He/she should know about any meds you take.
wwwdrugs.com says not to take flonase while taking Peg, Riba, and Vic
"GENERALLY AVOID: Coadministration with the hepatitis C virus (HCV) NS3/4A protease inhibitors, boceprevir and telaprevir, may increase the systemic exposure to fluticasone following intranasal administration or oral inhalation. Boceprevir and telaprevir are potent inhibitors of CYP450 3A4. Since fluticasone undergoes extensive first-pass and systemic metabolism via hepatic and intestinal CYP450 3A4, inhibition of the isoenzyme may significantly increase systemic bioavailability of the drug. The interaction has been reported in patients receiving fluticasone with other potent CYP450 3A4 inhibitors such as azole antifungal agents and HIV protease inhibitors. In 18 healthy subjects, administration of fluticasone propionate nasal spray (200 mcg once daily) in combination with the potent CYP450 3A4 inhibitor ritonavir (100 mg twice daily) for 7 days resulted in an approximately 25-fold increase in fluticasone peak plasma concentration (Cmax) and 350-fold increase in systemic exposure (AUC) compared to administration alone. These changes were accompanied by an 86% decrease in mean plasma cortisol AUC.".
http://www.drugs.com/interactions-check.php?drug_list=2009-0,2418-12110,1806-1159,3323-15313
I would check with the pharmacist at the pharmacy that is supplying the Hep C medication. They should have a list of all of your meds. Even if they do not have a list, they should be able to tell you if Flonase is okay to use with Hep C meds.
I would also check with your doctor. He/she should know about any meds you take.
wwwdrugs.com says not to take flonase while taking Peg, Riba, and Vic
"GENERALLY AVOID: Coadministration with the hepatitis C virus (HCV) NS3/4A protease inhibitors, boceprevir and telaprevir, may increase the systemic exposure to fluticasone following intranasal administration or oral inhalation. Boceprevir and telaprevir are potent inhibitors of CYP450 3A4. Since fluticasone undergoes extensive first-pass and systemic metabolism via hepatic and intestinal CYP450 3A4, inhibition of the isoenzyme may significantly increase systemic bioavailability of the drug. The interaction has been reported in patients receiving fluticasone with other potent CYP450 3A4 inhibitors such as azole antifungal agents and HIV protease inhibitors. In 18 healthy subjects, administration of fluticasone propionate nasal spray (200 mcg once daily) in combination with the potent CYP450 3A4 inhibitor ritonavir (100 mg twice daily) for 7 days resulted in an approximately 25-fold increase in fluticasone peak plasma concentration (Cmax) and 350-fold increase in systemic exposure (AUC) compared to administration alone. These changes were accompanied by an 86% decrease in mean plasma cortisol AUC.".
http://www.drugs.com/interactions-check.php?drug_list=2009-0,2418-12110,1806-1159,3323-15313
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