first set of labs for PSL 7977 and BMS 790052 study no interferon

[gonnabhepcfree]

When I started on Aug 3 my viral load was 2,355,050.99 units/mil  first dose Aug 3..labs on Aug 4- 4838...should have more results on Saturday..I am now allowing myself to get a little excited. Anyone thoughts would be appreciated for a one day drop of this kind..thank you ..

[attagrl]

@curiouslady - Well, at least 30 is still a long ways from 80+! I'm sure you'll be fine, especially when you consider how many big research universities are the study sites, and the whole process there moves incredibly slow due to the whole college bureaucracy. My mom (who is also doing the study, long story lol) and I were actually the first two to even be screened at our site, let alone start.

I'll keep my fingers, toes, and eyes crossed for you!!!

Oh, and @gonnabhepcfree, sorry for hijacking your thread. ;)

[curiouslady1]

attagrl I was told the same thing last week in terms of others being the guinea pigs but I was also told that 30 had started.  I am sweating acceptance right now and it will be another week before I find out the test results.  I was a little freaked by your post about the valium so I fessed up about having two bloody mary's two weeks before (believe it or not I was emailing mari at the time LOL).

[attagrl]

Oh, and according to the study coordinator, I'll be the first person with Genotype 1 to start. HOLY CRAP. That's some pressure. lol

[attagrl]

@mari: I know EXACTLY how you feel.

I found out about the study in early July, and I wasn't able to schedule screening until July 29th; during that time I was in a weird limbo wondering if the clock was going to run down before I would qualify for inclusion, trying not to get my hopes up. Then I found out I failed the drug test (due to a valium taken for a dental procedure a month before) and I nearly got booted -- just found out Monday that they decided to keep me anyway. It doesn't feel real yet, even though I have my appointment for D-1 on Monday, when I'll be randomized. I'm this weird mix of excited and terrified.

As for the waiting list, I can say that last week at my screening, the study coordinator said only about 18 people had started the study already, nationally. She said it jokingly, in that there's already a group of "guinea pigs" testing it out, so I'd know if there were any weirdo side effects before actually starting the drugs. :P Either way, it looks like they're not quite 1/4 full (at least, as of last week) so hopefully that means good things when it comes to you qualifying. *HUGS*

[curiouslady1]

I don't mean to burst anybody's bubble here but the study that gonna is talking about and which 2 or 3 other people are waiting to enter or applying to enter (including myself) has 6 arms.  Each arm has 14 people in it.  There are 42 with geno 1a or 1b, 42 with geno 2 or 3.  There is no arm for geno 4.  Once they have enough subjects (and they are currently actively recruiting and running subjects now) recruitment will stop.  Some entry criteria are evident from the clinicaltrials.gov web site . . . nobody who has liver disease, all subjects must be treatment naive, etc.  Some entry criteria are not so evident.  For example, the individual has got to be able to tolerate SOC which will be added to the other drugs if the person does not go UND within a specified time.  That means they have to have reasonable cardiovascular function, the absence of certain eye problems, no current drug problems, no underlying thyroid disorder, a BMI under 35 etc.  Study doc says they are particular at Phase IIa (that's why they are still looking) and much broader at Phase III.  

[Mari5116]

As for my beginning time line I can't say.  I've met with the trial folks a total of three times and spoken on the phone with them 3 more times.  They ordered preliminary bloodwork,  summoned medical records, etc.  They called today to reassure me I'm on the list and they will be conducting the trial and contacting me when they get the paperwork, as of yet they don't even have the consent forms.  
Somehow typing this is making it more real for me.  This in between place is kinda strange.