i think i have had viral breakthough due to huge interferon reduction at week 5

[alico222]

I think I have had a viral breakthough when I was reduced at week 5 to 90mg interferon, as I had night sweats etc.
Does anyone think this is the virus out in the open. Is it worth me carrying on with treatment.
Thanks
Alico.

[alico222]

i think paen has same instinct as me... what can i do now ?
I asked to go straight back up to full dose when i had asked around, so thats a jump back and had one sweat this week with increase.
have talked to consultant they are running scared and trying to do anything, its a terrible mistake, what can i do is there any point carrying on and putting my body under strain is this means the game is over.

Alico.

[nygirl7]

I haven't had them since treatment ended either.

I had to read the book somebody gifted me with it and I couldn't be rude to her now could I?   hahahahahahaha

[GSDgirl]

I also had night sweats prior to treatment.  Terrible drenching sweats.  Can't remember if I had them on TX but haven't had them since.

Denise

Deb, I KNEW you would read the book LOL

[Trish77]

"Occasionally there might be more to it than you're aware of. I don't really know all about this issue - unlike you apparently. Your certainty could lead someone to believe you actually know what you're talking about and that could be dangerous. For instance, when you start advising patients regarding treatment dosing. That's scary - for me anyway. "

I agree - there might occasionally be more to it than I'm aware of.  This is the first time I've ever heard a connection between night sweats and HCV.  I didn't advise her to stop treatment, nor did I advise her to proceed, nor did I post information on night sweats being a symptom of HCV implying a connection and leave it open to interpretation.  Her night sweats could be from any number of things.  Because she has HCV does not mean everything that happens to her will be HCV-related. I advised her to get a PCR as that being the only true measure of whether she's had a breakthrough or not.  I'm good with that advice.

I don't advise patients regarding dosing.  I state my opinion and what I would do like anybody else on this forum.  I tend to explain my opinion and what I base it on and I'm open to revising it based on information presented and responding to coherent challenges to the *information* presented with the goal of getting the information correct.  If you have issues with an opinion of mine on dosing, I'd suggest you say so on that particular thread where it's relevant and useful - particularly if you find it scary, rather than making vague innuendoes using someone else's thread on a completely unrelated topic.

[nygirl7]

Oh man I had the worse night sweats ever on treatment.  I would sit up and sweat would literally run down my body.  I would have to change tshirts and move to the other side of the bed then change the sheets in the morning. It got so bad I finally started sleeping on a towel which was easier to change then sheets.

I have never had night sweats in my life but definitely I had them constantly for 72 weeks on treatment and I have been SVR what 4 years now?

Heck Steven Tyler even talks about them in his autobiography (yes who didn't think I'd read it ;)

[mikesimon]

Maybe it's pure coincidence but after my second treatment when I cleared late I remember awakening with a night sweat. I hadn't had any sweats since I became undetectable which admittedly was late in treatment. When I woke with the seat I immediately worried about the virus. I was tested a week later and I had relapsed. During the next 8 weeks I had night sweats but a few weeks after staring my third treatment I stopped the sweating. I have never had another night sweat and that has been since 2004. Maybe it's just coincidental but I suspect that there is more to it.