incivek

[lilly12345]

Is anyone currently in treatment?  and if so did you treat before with relapse?

[newyorker719]

im treatment naive and starting week 5 w/ the incivek. how are your blood counts?..my wbc is down to 2.5 already. did you have a neg viral load at week 4?

[penn1023]

I was a null responder in 1994 so don't know if triple is worth a shot for me. I would like to wait and try this but don't know when it will be available and don't know what to do if I am stage 3 or 4 by my next biopsy in a few months.

http://www.trust.org/alertnet/news/vertex-4-drug-hepatitis-c-combo-shows-promise

[joemc34606]

I treated back in 2007 on interferon for about six months then went to infergen, went und on the infergen and did 48 weeks, but after I stopped it came back. So now im on my fourth week of triple therapy taking number 5 tonight.
Good luck Joe

[dixiechicdana]

I am treating with incivek. I am on 3 week. I responded with pegylated last time at 7 weeks. I relapsed. This is my 5th go around on various treatments sooo....

[spectda]

Most of the people on the forum seem to be treating with Incivek currently. The highest success rate for Incivek tx in trials is from the relapser group.

http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/AntiviralDrugsAdvisoryCommittee/UCM252562.pdf
"Telaprevir-based therapy demonstrated significantly higher SVR rates than Peg- IFN/RBV alone
• Among treatment-naive patients, rates of SVR24 were 72% to 79% in the telaprevir groups compared with 46% in the placebo group (P < 0.0001)
• Among the prior relapse population, rates of SVR24 were 84% to 88% in the telaprevir groups compared with 22% in the placebo group (P < 0.0001)
• Among the prior partial responder population, rates of SVR24 were 56% to 61% in the telaprevir groups compared with 15% in the placebo group (P < 0.001)
• Among the prior null responder population, rates of SVR24 were 31% to 33% in the telaprevir groups compared with 5% in the placebo group (P < 0.001)"

[Gerbils]

I am currently in treatment, week 8. Pegysys, ribavirin, and incivek. I am "treatment naive" as they say but have had hep c for probably 30 some years. Just found out Oct.2010.
G