Right can anyone give me any feedback

[hopeforall108]

I posted a couple of questions bout anyone one here hearing anything bout bavituximab or chronvac c and nobody replied, I'm startin to feel lime a leper? Anyone any feedback? Oh and how many of you really brave souls on here who treated and got svr havehad pcr's done on liver biopsytissue since? Thanx xx

[Bill1954]

Here’s the link again… it didn’t post the first time:

http://www.medhelp.org/health_pages/Hepatitis/Occult-Hepatitis-C/show/54?cid=64

I’ll try to take another look at Chronvac a little later,

Bill

[hopeforall108]

Thanx I should have mentioned that chronvac c stimulates a hcv specific t cell response, it's a DNA vaccine and it's delivered via a new method whereby the muscle injected is given shocks it dramatically increases the uptake of the vaccine to your cells

[Bill1954]

Hi there,

And welcome to the discussion group. There’s a section on this page on persistent/occult HCV; you can find it in a box called ‘Most viewed health pages’, located in the right-hand margin, or go here:

While all this is interesting from an intellectual perspective, it doesn’t appear to have much impact on the clinical outcome of HCV. The durability of SVR has been well established; I personally don’t see this as much of an issue for patients… at least at this time.

I have heard of ‘Chronvac’, but haven’t followed up on it seriously. It sounds interesting; especially since the presence of antibodies doesn’t confer immunity to HCV virus.

Good luck to you; if you want to pursue the occult/persistence issue here, you might want to contact either ‘TnHepGuy_’ or ‘Doubledose’; they both contribute a lot of energy to these phenomena.

Take care—

Bill

[hopeforall108]

Well please keep us posted and be sure to insist they to OCR test on your liver samples and not just fibrosis scores. Good luck. Oh and by the way be sure to check out the combined trial done in new Zealand it was a trial with a protease inhib and a polymerease inhib without soc hugh rapid viral decrease and the language being used by the researchers and companies invovled is so positive. Very unlike them in my experience. Right back to my xbox.

[hopeforall108]

Thanx peps, 1 st figuy those egg heads who thankfully have nothing to do but research this nasty little beasty (hcv) have recently found that some svrers have still got beasty RNA in their livers and peripheral blood cells, so I was asking to see if anyone here had gotten similar news? Just try to get a feel for the extent of the thing. And as for the drugs I mentioned just goodle em, one chronvac is a theraputic vaccine shows massive promise. And bavituximab is a monococol antibody, it basically attaches itself to fats that pushed to the outside of infected cells and flags em to the immune system for destruction. Cos it dosent actually attack the virus, viral breakthrough ain't expected it appears to work on most single stranded viruses and cancer tumours too. The u.s. Military invested $44.5 million in it as a possible anti biological weapon tool. Google it and happy reading. As for the whole hcv possibily still present after svr go to hepatitis central latest news, one report was postedthere.

[FlGuy]

I agree. And, I would wonder about any doctor who would do it.

[GreatBird]

If it isn't medically necessary, an insurance company may decline to pay for a biopsy.

[newleaf09]

Personally, I never heard of either of those drugs.  A web search would likely bring them up.  I only very recently finished TX but don't intend to have a PCR once I am released.  I'm in a trial, however, and think they will do PCR's after the 6 mos. mark so they can more thouroughly prove that 28 wks. works.

I absolutely do intend to have a follow-up biopsy 1 yr. after EOT.  Nurses said 6 months but I will wait the full year to assess all the repair that I can.  I will follow up with my GI to monitor my blood for several years.  Bloodwork can tell the story of liver damage, once you learn how to read it.

Doctors don't insist on follow-up biopsy.  It's a personal decision for your own peace of mind.

[AngelaNicole]

i havent heard either of those names.  my Dr in Boston Dr. Afdal, is one of the leaders in hcv treatment and working on cures.  hes only used numerical names of new drugs and some older ones that are in trials or at the end of trials.

sorry no help here.

[FlGuy]

Once a person has treated and attained SVR for hepatitis C there is really no reason for a biopsy unless for medical evaluation for another reason.  Many, if not most, have a biopsy upon diagnosis because liver damage is a component of a full assessment.  Assuming that svr is achived, a biopsy would be more of curiosity than a medical necessity.  Post treatment, liver function can be ascertained by other non-invasive means and observations.  I sure would not allow a biopsy.  Now, a fibroscan might be a thought...But, I would not throw good money against it. As long as I'm living and breathing I'm assuming the old liver is still functioning.