Thank you Bill
I will check it out!
Happy New Year!
Hi Candyce,
I’m not sure there are any discernable, end-point differences between Pegintron and Pegasys.
If you go to this site:
http://www.hivandhepatitis.com/hepatitis-c
and use their search engine look for ‘IDEAL’ study results. I’m trying to do that right now but the engine doesn’t seem to be working; perhaps it has a hangover from Christmas dinner last night or something :o). Try later and I think you’ll find similar efficacy between the two products across genotypes. This is a good reference site regardless; you’ll want to bookmark it for future use.
Regarding ribavirin I agree with others; there should be letters of bioequivalence available from various manufacturers and again, no clinical difference in product efficacy.
--Bill
Thank u both for the links
Very informative!
On the "Clinical Care Options" web site there's a nice slide presentation called,
"On the Front Lines: Battling Chronic Hepatitis C Today and in the Future" download Slideset: On-Treatment Management of Hepatitis C Patients. Free registration. Starts on slide #24.
Regards
Charlie
My understanding is the active ingredient of each is the same, but just a different brand name by different manufacturer.
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I think you knew, but for clarification, I was referring to Ribavirin, not interferon. There are difference between Pegasys (peginterferon alfa-2a) and PegIntron (peginterferon alfa-2a).
http://www.natap.org/2008/EASL/EASL_86.htm
http://www.medhelp.org/posts/Hepatitis-C/Peg-Intron-or-Pegasus/show/87583
http://www.aidsmeds.com/articles/hiv_pegasys_pegintron_1667_17850.shtml
Pegasys (peginterferon alfa-2a) is available as either 0.5 ml preloaded syringes or 1.0 ml vials that have to be loaded by you into the syringe. Both contain 180 ug of interferon. I received one shipment of the 1.0 ml vials and didn't like the extra hastle and volume to deliver. I requested to receive the 0.5 ml syringes from then on. I agree that the 0.5 ml preloaded syringes are easier to deal with and the smaller volume is also nicer.
Thanks fly cyclist I think I am going with Pegasus since md said and the pre loaded
Happy holidays!
My understanding is the active ingredient of each is the same, but just a different brand name by different manufacturer. I recall some are available in different doses, so if you needed to do a dose reduction this could be an advantage.
Thanks
Just checking on the riba to get the most bang for the buck!
I was interested to find that there was such a big difference between peg inton and Pegasus though
I am 1b TT so every tiny percentage pointed in my favor may help :-)
There all the same as far as effectiveness comes in a generic form as well