slight elevated SGPT,Gamma GT & Direct Bilirubin

[owel]

i am 36 years old, i drink alcohol too much when i was the age of 20's ,  and i am taking medication for my GERD ; pantazol, motilium and other antibiotics like tetracycline. i have done a LFT yesterday and  all are within the normal limits except for the Gamma GT (73), Direct Bilirubin (.75) and SGPT (50). and sometimes i can feel a slight pain in the left upper quadrant of my abdomen. Can you give me some diagnosis pertaining this LFT results?
Thanks....

[joachim2007]

i think the ranges you are referring to are "total bilirubin".

However, owel was referring to *direct* bilirubin, which should be a smaller fraction of it.

Interestingly enough, it seems there is no complete agreement in the scientific community as to what exactly the upper limit of direct bilirbuin should be. Maybe it's because there are different testing methods out there, and therefore ranges can go from as lows as 0.2g/l (like in the lab that i use) to 0.6 or even 0.8g/l  (as reported in a lab survey in NYC [1])

so, best idea would be if owel could compare her value with the upper limit defined by the lab, and discuss the meaning of it with a doctor who can interpret it.

[1] see Schiff's Diseases of the Liver, page 225

[Jakied]

The normal range of bilirubin is 0.1 to 1.2 or so.  your Ggt and alt are at the high limit of normal.

[joachim2007]

hi,

i think it would be reckless to suggest any diagnosis based on this limited information.

You need to see a physician to systematically analyze your case, make a full anamnesis including:

- do you drink any alcohol (as it can raise specifically the GGT levels)
- might the med's you take interfere with the GGT levels (eg. the pantozol)
- a repeat test, incl screening test for viral Hepatitis and a complete liver panel (with more parameters) would als be helpful. Perhaps your liver values are going back to normal while we speak.
- further the doc might want to order an ultrasound to see if your spleen could be responsible for the ULQ pain of your abdomen.

One good thing that i noticed is that your GOT is not elevated - it is better to have GPT higher than GOT rathern than vice versa. (google de ritis quotient). But since i am not a physician, i have no right to claim that this means anything, and i cannot judge how severe or not your bili elevation is.

--> best wishes & good luck with the follow up with the doctor!