telprivar relapse

[Debbie556]

I posted this morning about my husband being told at wk 24 he had not met the req. to continue in they study or he had e RVR. We know he was non detectable at week seven and have been told up to that point that he was doing "the best in the study" all his levels that they did give to his Dr were great. Monday we went in and was told he relapsed and was only going to do the follow up. I have read all the paperwork from Vertex and do understand that they can stop the treatment for two reasons : one you have relapsed or you have no dectable level in you system and they are just monitoring you for the next 48 wks.  They also say you will remain on treatment for the full 48wks either way unless you are clean.I am not sure if his Dr just said he relapsed at this time because we did get blood work done at 7 wks and told him he was clear by the outside testing. We are getting him tested asap either way. I just don't understand because this is a double blind study and his Dr does not have the actual results....

[jmjm530]

If he did only recieve Telepravir for 12 weeks and a further 12 weeks of SOC, he would have been in the active comparator arm and there is a good chance that he was taken off tx at this time because he remains undetectable.
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This is the most likely scenario.

[jacksonblue]

thats what i think

[Evangaline]

The only way you are going to know for sure before the end of the trial, which won't be for some time yet is to get another PCR and its results as soon as possible. If it comes back und, you'll know he responded, if not perhaps you can convince your Doc to put him back on tx with peg intron immediately.
I find it confusing that your husband was on Telaprivir for that long, the study calls for it to be given only for 12 weeks. If he did only recieve Telepravir for 12 weeks and a further 12 weeks of SOC, he would have been in the active comparator arm and there is a good chance that he was taken off tx at this time because he remains undetectable.
Evangaline

[Debbie556]

kinda makes you feel like a mushroom keep you in the dark and feed you alot of s**t.
Make sure you eat well it is so important..Drink alot of water and if you can find it drink the orange vitiamin water it helps keep your immune system up.

I know the Dr kept telling me he wanted to talk to me after the study because my other half did better than everyone else so he wanted to know what I did for him. That being said. If you want I have my own ideas as to what to eat and what to do to make it as easy for you as it can be. Let me know if you need anything ***@**** it probably the best way to get me.. Good luck

[jacksonblue]

thank i may need some tips i also treated with intro 3 shots week t rib i found it nastier then this i am very lucky this time around my neighbour is a nurse and comes over every tuesday to give me my shot and stepson does all grocery shopping even cooks me dinner 3 times week  be well deb try not to stress

[Debbie556]

the scary part for him was his viral load was " Very" low yet he was border line for stage 4 liver disease. What I have learned is that the faster you respond the greater your success rate for cure. I know that he passed the protocol for week 12 also it is just strange how they word things and how they keep you in the dark for s much of this but if the telprivar works then it will be worth it for so many people.. I wish you all the luck in the world and anyone else going through this