telprivar relapse

[Debbie556]

I posted this morning about my husband being told at wk 24 he had not met the req. to continue in they study or he had e RVR. We know he was non detectable at week seven and have been told up to that point that he was doing "the best in the study" all his levels that they did give to his Dr were great. Monday we went in and was told he relapsed and was only going to do the follow up. I have read all the paperwork from Vertex and do understand that they can stop the treatment for two reasons : one you have relapsed or you have no dectable level in you system and they are just monitoring you for the next 48 wks.  They also say you will remain on treatment for the full 48wks either way unless you are clean.I am not sure if his Dr just said he relapsed at this time because we did get blood work done at 7 wks and told him he was clear by the outside testing. We are getting him tested asap either way. I just don't understand because this is a double blind study and his Dr does not have the actual results....

[Debbie556]

Thank you... keep up with what you think is right for you.. 9 yrs ago when my husband was fist diag. the treatment was three shots a week and alot more riba. than now so do what you feel is right for you. He started at 202 lbs and is now at 170lbs they never wanted to change his meds. Keep up the good work.

Not to blow smoke up my own butt ----my Hubby's Dr wanted to know what I was doing for him to keep him so healthy. said he did the best out of the whole group when it came to keeping his "good" levels up. Let me know if I can give you any "tips" and all the best for you in getting to neg....

[jacksonblue]

your husband could very well been neg week there is another here same trial as you went fron 10 million to neg i believe week 3

[jacksonblue]

if viris was neg at week 4 or sooner and then again at week 12 and remained that to week 24 done with treatment
if viris neg between week 4 and 12 and remains so you go to 48
if on placebe must have 2 log drop week 12 or done then must be neg week 24 or done
any viral break through you our done i hope i have explained it i am a little brain dead right now in week 17 i dont think would drop you for your own testing i was told to reduce rib after dec 30 test and took some advice given here and had my own cbc done wich i gave to hospital  never dose reduced any was able to carry on

[portann]

So you're just going to have to wait, since it could be one or the other in respect to why he stopped at 24.

The doc doesn't appear to know what's going on, so I wouldn't take his 'relapse' talk to heart (not that anyone can be level-headed in such an ambiguous situation).  

BTW, did the doc break protocol by saying you 'relapsed' when he was required to not specify anything other than what was in the letter?

I'm with Zazza and the others who feel hopeful.

[Debbie556]

Stats for my Husband: 53- Naive for treatment ,3-4 stage for liver disease, found out 9 yrs ago had hep-c

[Debbie556]

was disclosed "Off the record" before he was told about finishing at wwk 24