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Avatar universal

Building Organs

Not a question...just some info...saw this on the 17th on MSN and some of the other media outlets:


On June 17th a story ran carried on AP and most media coverage that covered a story about Dr. Anthony Atala

of Wake Forest North Carolina was in a photo showing him holding a prototype of a kidney.  

Growing lungs and other organs for transplant is still in the future, but scientists are working toward that goal.

A 3-D printer builds prototype kidneys.  In several labs, scientists study how to build on the internal scaffolding

of hearts, lungs, livers of people and pigs to make custom-made implants.  

There's a really long web address....I found it just by searching "growing organs in lab in north Carolina".  

Then of course there is the usual reiterate... should this really be done...isn't against this and that...you know

those people are sitting on a transplant list waiting.  
Best Answer
Avatar universal
OH did have her old liver entirely removed, and she received 65% of her daughter's liver, so she had a live donor liver transplant.  Some transplant centers do live donor liver transplants, and some do not.  I think the confusion is just with the word "partial".  OH's daughter donated "part" of her liver to OH, so OH received "part" of a liver.  She went out of the country to have her live donor transplant, but some centers in the US do this type of transplant.  I have not researched much on live donor transplants, because 1) my husband currently has compensated Cirrhosis, and 2) the transplant center near us, where he currently receives care, does not do live donor liver transplants.

Heart, I think you could have either a live donor liver transplant or a cadaver liver transplant, but many centers, perhaps yours, do not do live donor transplants.  I think you may have misunderstood something regarding the reason why you can't have a live donor liver transplant.  In your post above you said you were told that "your liver was too far gone and it would be too dangerous".  So far as I know, having your liver be too far gone would not prevent you from having a live donor liver transplant.  It is more likely that your center simply does not do live donor liver transplants.  However, "it would be too dangerous" probably refers to the risks involved for the live donor.  I believe that the primary reason that many transplant centers choose not to do live donor liver transplants is the risk to the live donor, at least that is what a transplant hepatologist at the University of Washington Medical Center explained to me.

Can-do, I think Heart is using the word "partial" to explain that OH's daughter donated part of her live liver to OH, so OH received part of her daughter's liver.  I suspect that her liver transplant center does not do live donor liver transplants, and that's likely why a live donor transplant is not an option for her (don't know for sure, but that's what I am speculating).  As Heart said above, she has decompensated Cirrhosis/ESLD, so remember that with her symptoms at that stage, it may be difficult at times to process, understand, remember, and express some details of a lot of information.  Patience, grasshopper!

I will check around and see which centers in the US do live donor liver transplants just to clarify this question.  In the meantime, Heart, you are doing everything right for your specific situation.  For you, it's hurry up and wait!

Now both of you chillax (please)!

Advocate1955
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4670047 tn?1375730401
I'm wondering how this is determined, "partial from a live donor" or "transplant".
I'm just not understanding how Orphanedhawk was so close to death and a partial was able to save her? It must be as you say __each person is different.  
Yes those numbers are so sad!! :(





Helpful - 0
4670047 tn?1375730401
I didn't understand post ?

I'm always curious about this, but don't quite understand this statement, I have never heard it before.

At stage 4 with decompensated liver I would need a whole liver transplant not a partial.
Helpful - 0
Avatar universal
I don't understand.  Maybe I am not saying it correctly.  Have never professed to be a medical expert on any of this and all I can do is relay what my experience is.  I believe what I meant was Orphanedhawk had a "live" donor "partial" transplant...and it worked for her at her stage which was dire.  

Believe me I have pestered Hector with all sorts of outlandish reasoning but it comes down to the fact that I need to do a liver transplant.  They won't consider doing a "live" donor  transplant for me.  

Am stage 4...with end stage liver disease (ESLD) and my liver is decompensated (dying).  The decompensated area (about 85%) will not regenerate or rejuvenate.  One can not live for long, especially as the cirrhosis continues on 10 - 15% of your liver.  

By the time you get to stage 4 with decomp a large portion of your liver is already dead.  It is their protocol at this point, for me, to do a whole liver transplant.

Others might have different experiences and I would like to hear all of them.  Through this site I have met many strong courageous people who give me helpful information all of the time.

All I know...the numbers are just mind boggling as to how many people are waiting for a liver on a transplant list.  17,000.  All with different stories I am sure.  So I am not here to speak for 17,000 people....just to say...come on medical world....do something....this is crazy.
Helpful - 0
Avatar universal
I am always curious about this, but I don't quite understand this statement, I have never heard it before.

" At stage 4 with decompensated liver I would need a whole liver transplant not a partial."
Helpful - 0
2059648 tn?1439766665
Sorry for your pain.  I do know the difference between decompensated vs.
compensated.  I won't aware the topic was transplants.  I wish you the best and hope you are one of the lucky ones.

Best To You
Helpful - 0
Avatar universal
according to my liver transplant doc a liver that is in decomp will not rejuvenate... I notice that posters sometimes forget there is a difference between compensated and decompensated when it comes to cirrhosis.

there are 17,000 people sitting on the liver transplant list...only 4,000 will be able to get a transplant out of those 17,000.  Then there is a percentage of rejection for the ones who are transplanted.  

my only purpose was to show that the medical field is working on making artificial organs which would make approximately 13,000 people who won't get a liver this year very happy.   This is years and years away but should be noted that a biotech company in California has already perfected an artificial ear so it's only a matter of time.

the 17,000 people sitting on the transplant list are in a position where their livers will not rejuvenate so if the scientist's ever perfect this technology it would be good news to them.  

I have stage 4 ESLD w/decomp.   My liver will not regenerate/rejuvenate.  You sound like my PHd son who keeps saying to me, don't worry Mom. He keeps telling me the my liver can regenerate....don't know why he doesn't get it....he's smart enough so I think it's denial that his ever strong Mom is really ill.  Guess he'll get in when he sees me in the ICU after my transplant...if I get one before it's too late.

And believe me...I have pursued every avenue to just avoid getting a transplant....no one who is on the transplant waiting list wants to be on that list....if there was a way to rejuvenate a decompensated liver I am sure they would.  Having a liver transplant is not the easy way out.  The surgery is no fun...the scar is wild plus all the side effects and the meds you have to take for the rest of your life, and this is barring complications.

No one can deny that liver, kidney and heart transplants are life saving and anyone who is very ill who is very lucky to get one.  Plus, we have to remember for this individual to get a transplant most likely someone had to die.  Of course there are live donor to donor transplants for the liver and kidneys but there are restrictions and guidelines.  At stage 4 with decompensated liver I would need a whole liver transplant not a partial.  

Each individual is different.  Orphanhawk was lucky she had a donor to donor procedure that went well...we have had many others on this site who have had to have complete replacement.  NUOS has strict guidelines they follow especially if your HCV is still active.

Hector's post has good info on the difference of decomp vs. compensated, what can rejuvenate and what can't.  
Helpful - 0
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