About 6 months ago, after a long night of having sex with my partner, I began to have some vaginal irritation. I saw my gynecologist because the irritation began to worsen. She done a swab & a week later informed me that I had herpes. The partner I had been with of course insisted he did not have herpes. After several antibiotic treatments, as a precaution before the diagnosis, and after taking Valtrex and using Zovirax cream, the irritation stopped. I haven't had any other problems until recently. After another long night of continuous sex, much like before, I was a little sore. The soreness got worse & some redness appeared, but no blisters. I saw my new gynecologist & he said the redness could possibly have been from an outbreak & told me to increase the Valtrex that I had already been taking until the irritation was gone. I took it upon myself to use the Zovirax cream that I had left as well. This time it does not appear to be responding to the treatment. Actually, where I applied the cream has, in a matter of hours, developed into large, very red, & very itchy spot just inside the opening of my vagina. It appeared to have healed, so I had sex with my partner & the irritation immediately returned. I am wondering if the herpes diagnosis was incorrect. I have never seen any blisters, & both times the "outbreak" developed after continuous sexual intercourse which caused a lot of friction. Is it possible that there is something that is causing the vaginal skin to be extremely sensitive? I have had a blood test that showed positive for herpes simplex 1 & negative for herpes simplex 2, but I have always been very prone to get fever blisters orally.