atypical urothelial cells, joint pain, weight loss, frequent urination

[elmosmom]

I am a 57 year old female with migratory joint and muscle pain. It ranges from mild to debilitating. I have had this for several years.  The doctor says I have rheumatoid arthritis even though the blood tests do not show the antibodies. His diagnosis is based on the finger and hand deformities in one hand and the painful joints and swelling of joints. I also have experienced weight loss, from 150 to 120 pounds in 6 months. I also have very frequent urination, which I have experienced for several years.  Blood was found in a recent urine sample, another sample showed atypical urothelial cells. Cystoscopy was normal.  Abdominal ultra sound was normal but air in intestine blocked the technician from seeing more. Pelvic ultra sound scheduled.  Could cancer in another area of my body cause atypical urothelial cells in my urine? Would this be indicative of a more advanced form of cancer? Can I have atypical urothelial cells in my urine and not have cancer?  Thanks, am concerned.

[frankmichaels]

Dear Doctor
Reference - atypical urothelial cells, joint pain, weight loss, frequent urination
by elmosmom, May 23, 2008 09:14PM

My wife has been suffering from migratory joint pains (one can see a red line radiating along her wrist till her arm) and they do show up more severely before her monthly cycles.

Elmosmom's symtop with respect to this caught my eye and was hoping yud throw some light on it.

Thanks ad Regards
Mike
***@****

[Dr_Aparna]

Hi,
Atypical urothelial cells in the urinary sediment are a common finding. They may occur in a variety of benign conditions, but also in low-grade tumors. Computerized image analysis of atypical urothelial cells has shown that they could be separated into 2 groups. One of these shares cell features with benign cells and the other with malignant cells.
Cancer from another area cannot be the cause for its presence in the urine.How-ever this does not mean you have cancer of the urinary tract .
Coupled with the fact that you have experienced weight loss and frequent urination it may be significant.
Have you got your blood sugar testet?These same symptoms can be seen in diabetes too.
ref:http://www.aqch.com/toc/auto_abstract.php?id=22951