high creatinine level after 8 year of kidney transplant

Question

i can not good speak engelish.i am sorry
i have Alport syndrome and get kidney transplant(8 year)
 but from last few months :
creatinine level: 4.5
urien: 155
bp: 13/8
Protein in urine( 24 h) : 2000
my drug:
tacrolimus
cellcept
prednisolone
my kidney working:27%
how  i can Reduction my creatinine level ?
very thank

Marina_busybee · Accepted Answer

I'm  so  sorry  to  say that if  this has  been  a  slow  creatinine  rise   (chronic)  then  no,  there's  is  no  way  to  reverse the  damage.  However, you  can  help  maintain  it  where  it's  at.
Avoid  as  much  sodium  as  possible,   keep  blood pressure  close  to  normal  levels  (if  that  requires  medicine,  then  take  it  as  prescribed),  drink plenty of  fluids  (  at least  64oz/day)   do  not  take  any  OCT  NSAIDs (over  the  counter pain  relievers,  which  contain  ibuprofen,  or  aspirin) 
 here's  a list:   http://www.lyberty.com/encyc/articles/nsaid.html 

Keep an  open  communication with  Drs   as  what  to  do  or  how  to  maintain your   kidneys  at  the  level they're  at.

Take  care!

Marina

electronicavr · Answer

my donor was 31 year and that time i have 23 year.
this time i have 31 year.
is there any drug to return my kidney to normal working?
please send for me any link of web page that can help me.

Marina_busybee · Answer

An  infection will  definitely  raise your   creatinine,  especially  if you're  taking  oral  meds  and  even more  when  Drs  give you  IV  antibiotics.   Yes  antibiotics  can  be  very  toxivc  to  our  system,  yet  they  work  to kill whatever  bug  is  hurting  us.

How  old  was your  donor?   Was  your  donor  alot older  than you?    is  that  what your  Dr means  by  "your  kidney  is  old" ?
 
Take  care!   :)

Marina

electronicavr · Answer

thank you for your Attention:
What  do your  Drs  say about  that? he say that your kidney working 27% and your kidney is old
how   long has  this  been  going  on? 2 week ago my creatinine  is 3.5 and next become 4.2 and next 4.5
 Are you   taking  any  antibiotics,   diuretics  or  any  new  drugs  regimen? no but i have a Infection 5 week ago and i have  a Hospitalization.
 Are you  drinking  plenty  of  water? yes
my tacrolimus level is :22.5 and my Weight is 75 kg ( 31 year)
i Consume 3 tacrolimus ( 1 mg)  in 24 hr
i do not drink caffeine.
thank you

Marina_busybee · Answer

Sorry  to  hear your  kidney   creatinine  is  rising.
What  do your  Drs  say about  that?            how   long has  this  been  going  on?    Are you   taking  any  antibiotics,   diuretics  or  any  new  drugs  regimen?    Are you  drinking  plenty  of  water?
You  know  that  tacrolimus  is  a  great  and  powerful   drug  which  prevents  organ  rejection.   BUT, if  the  tacro  concentration  in the  blood  is  too  high, then  it  can  damage  the  kidneys.
You need  to  make sure you  stay  well hydrated,  drink  lots  and  lots  of  fluid,  try  to  avoid  caffeine  or  limit  it,  because  caffeine  causes  dehydration.

Good  luck!!

Marina

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