2nd month of treatment - resurge of symptoms, argh

[Hope75]

So I'm on my second medication break (3 weeks on, 1 week off) and now I'm having more symptoms.  Twitching, burning ankles, cold feet, and muscle spasms in my back and left leg.  Not sure why?  I am on a med break this week.  This is always a let down, just when I start feeling good again - it's back.  When will it end??

[Hope75]

I was tested for coinfections by Quest - negative.  Igenex - CDC positive for Lyme IgM.  But, my LLMD assumes you have coinfections and treats for them.

So, my treatment has been Doxy, oral, 400mg/day from May - Dec.  Then, since Dec. - azythromycin, Omnicef and rifampin every M, W, F and Flagyl on Th, F.  This is pulsing, I believe, that my LLMD has me on.  Also, supplements (lots) and gluten free diet (that I've slacked on lately).

I can't help but get discouraged, because I was doing so well and then bam - symptoms again.  It has always cycled like this, about every six weeks.  After being treated for 2 months, I was hoping it would never come back.  As I'm typing, my thigh is twitching like crazy and my ankles and top of my feet are on fire.  Ouch.

Is it too much to ask to see an improvement by now, after all the $$ I've sunk into this?  I know Lyme doesn't know what $$ is....but I sometimes question, not if I have Lyme, but I question if these particular symptoms are due to Lyme.  Wavering!

[holdingon2hope]

I wish I could tell you. I have been through several years of several different treatments and after a couple weeks off the treatment my symptoms always return. sometimes even worse because of the rebound affect. What type of treatment are you getting? What symptoms of Lyme have you experienced?

[JackieCalifornia]

Hope,

You've been a member here longer than I have ... and I don't recall your particular diagnosis.  Lyme, or Lyme w/coinfections?