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904511 tn?1251219733

TESTS??? KAPPA???

hi,
my rhuemy ran a bunch of RA and Lupus and inflammation test along with ones he didn't mention to me. I requested my results and my doctor wont be in town for a month. I am having a hard time figuring out what some of them are for.
7Has anyone had a Kappa or Lambda light chain test? My Kappa was 432 and range is 74-295. Also my Kappa/Lambda ratio is 2.8 and range is 1.3-2.8. A tad elevated.
Along with these I got a Rheumatoid Factor IgA is 9 range is >6 positive.
my sed rate is elevated at 39, my CRP is elevated and same with my Globulin. All inflammation markers.

My C3 Complement Component was normal same with the C4
I have had a CDC positive IgM for Lyme disease but the doctors think it was just exposure since my IgG was CDC negative with 4 of the 5 positive. Then I had a very general lyme test negative after that.


Has anyone been tested with the Kappa or Lambda or have any info as to what they tell?
6 Responses
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314892 tn?1264623903
My Lambda was normal and hence, a normal K/L ratio. 2.2 range (0.8-4.0)

This was so long ago, I dodn't ask questions, just believed what I was told...
Helpful - 0
314892 tn?1264623903
I have been looking for the answer you ask about the Kappa Protein test
I had bulls eye in 1994, followed (like you) by vertigo attacks and swollen knees.

This has waxed and waned over 15 years. All Lyme tests negative, except the 41 band on the western blot.

My Protein studies back in 1997- when misdiagnosed  w/ Meneire's Disease were as follows:

Kappa   1300.0 High     range (574-1276.0)

Not very high, but it stands out. I have researched, but cannot make sens of it.
Helpful - 0
904511 tn?1251219733
Thats a really good outlook that I didn't think about. That the Lyme disease could be messing with my white cells. Cuz bB can get into your plasma too right??? I have an appointment on Wednesday with my normal doctor to go over the test results to see if he wants to set up a referal with an oncologist. But my insurance dont cover any of the LLMDs I've found so, I wanna get all of my facts straight before I go spending hundreds of dollars on an appointment i may not need. I just can't figure out why the doctor who ordered the tests wont even talk with me. I couldn't even get a phone consult or anything just to ask him the question if the Kappa test is exclusive to cancer or if there are variables that can make it positive as well. I wasn't asking him to go over my medical file with me. Just that simple question. You know what I mean?
Helpful - 0
Avatar universal
Wow, that's a lot of information you had unloaded on you.  

My personal reaction would be to follow the LLMD's advice and to ask him about the 'blood cancer' diagnosis, and to guide you to a doctor who can oversee that part of your care in coordination with the LLMD's work on your Lyme.

If you indeed have Lyme as the tests seem to indicate, would your immune system not respond to the infection and perhaps cause strange results that could look like cancer of the blood?  That's a question I'd ask the LLMD.

Good luck, let us know what happens and how you do.  Take care!
Helpful - 0
904511 tn?1251219733
The ID doctor couldn't speak english the greatest but what I got from the "exposure to bB" was that I had been bit by a tick that was not carrying the live infection only the antibodies from a recent infection and so then I made lots of the IgM antibodies to "fight" the dead infection from the IgG antibodies from the tick. But to me it seems that I could have had to been bit a LOT of times by this type of dead infection tick. Or maybe what he was thinking is that I had lyme, got no symptoms from it and fought it off just with in the last few months and it was just a coincidence that we ran a Lyme test. I really honestly dont know. My LLMD thinks it's a typical response from a CDC doc and that I need to be started on treatment right away. But now I tested positive for blood cancer so I think I need to figure this out first. Cuz this type of cancer is in the white blood cells so it will effect your antibodies so that could be why my lyme titers dont make much sence. I dont know  though. i just wanna know if some people with lyme or lupus can test positive for this kind of cancer. '
Hey if you have anymore questions just hit me up. I research SO much about lyme and such illnesses.
good luck!
Helpful - 0
666921 tn?1254990618
'just exposure' - to lyme - what does that mean ?

I am sorry I can't help with your results info.

best wishes

gorbs x

Helpful - 0
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