What else causes low CD57?

[Todd36]

it seems like there are a lot of people with questions related to CD57.  It would be nice to have a doctor give an overview of the marker, eh?

anyway, i got my CD57 back today and I clocked in at 40 but I'm still waiting on western blot.  My dr said that it wasn't that low but it was lower than average.  The scientific literature says 60-360 is the normal range.  My white blood cell count is normal, EMG and NCS are normal, brain and C-spine MRI normal, and neurological exams are normal, but I'm still dealing with strange, diffuse pain and muscle twitching with the recent development of eye and throat pressure.

Besides lyme disease, what else does a low CD57 point to?  I know it can be low for HIV but that's out of the quesiton for me as I've been married for 10, and I had an HIV test before I was married and I haven't have blood transfusion.  SO...what else does a supressed CD57 indicate?  High CD57 is indicative of cancer, but low????

your input is appreciated.

Thanks,
Todd

[mojogal]

I read an article about it not being reliable any more but in my case it matches the way I feel.

[Ephedra]

According to my LLMD, biological toxins can lower it i.e. mold toxicity and so can viruses.  My CD57 just came back at 8 as well.  It began about 6 months ago at 5, so I wonder if I'm getting better even though I don't feel like it.  My CD57 is the only lab that is out of range, everything else keeps coming back normal.

[mojogal]

No, it wouldn't cause it too be low. Mine is 8 and I am very sick but that is not always the case.

[ramchargfer]

does beta seron for ms cause the cd57 test to be low? I was off the beta for a month befor I took the test? it cam back in th teens 17

[melissasmiles]

. a excellent lymes doctor i use is Dr. Kalb in Franklin Tennessee, he combines state of the art medicine with holistic medicine..he has literally saved my life and is currently treating me for lymes. I suffer from lymes carditis and my fatigue was extreme..as well as severe memory loss. i had had gastric bypass 6 years ago so my stomach could not handle doxycylcline..so he put me on ceftriaxone injections i gave myself 2x daily via a port in my arm...it literally saved my life..and no side affects from the ceftriaxone either. my insurance paid for a couple months worth but then i had a pharmacist order it for me ..it came in a powder form in bottles..i only had to add saline and it worked great and only cost me a co pay..for some reason my insurance paid for it..but would pay for the balloon type anymore...they would have cost me $1200 to continue using those but mixing my own was super easy..just a little more time consuming.  FYI the balloons are just a round baseball size ball with ceftriaxone premixed in it..you just hook it up to your port and then you can stick it in your pocket and go about your business..when its empty you just unhook and throw it away...very cool invention..beats having to set with your meds trickiling into your arm via a IV pole...not being able to move for 30 min or longer... how is the bacillin LA shots working?  

[cave76]

"About the CD57 test----- if you have to pay for it out of pocket, I'd save the money.  Before taking it, if you do, ask yourself why  so many people have a 'normal' test result while feeling like death warmed over. Then ask yourself why so many who have almost NO symptoms have tests results that are near zero."

But coincidences DO occurs, I know.

This thread is full of conjecture and mis-information about the CD57 NK cells.

One of the responders on this old thread is a person who relies on LymeMD as the source of all wisdom who said in his blog:

"Unfortunately, I am left with the conclusion that it [ the CD57 test] has been of very little help to my patients."

Hmmm.

http://lymemd.blogspot.com/2009/01/cd57.html

Read the entire entry on his blog.

Then go to other forums and read all the varied responses that people have about the CD57. I have------ in toto------ throughout the years. It does seem as if physicians have only read Stricker's article once and believed it and never once read what the patients report. Even Burrascano waffled a bit on it. Just a bit, but how could he waffle more since he's praised it in the past?

Yes, some people will say "my CD57 reflected exactly how I feel".
Almost as many will say "my CD57 reflected the exact opposite of how I feel".

The CD57 may have some worth---- after all, data is data. In the future.
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From the link you gave us Ginger Savely said, about the CD57;

start snip

CD57 could be impacted by Bartonella, Babesia, mold, viruses, PANDAS/PANS, Mycoplasma, and Chlamydia.

Mentioned a low CD57 in one case with Chlamydia pneumoniae with no Borrelia infection.

Does not appear to be reliable in monitoring progress in the short-term.

Should never be ordered more than every 6 months.

Dr. Jones does not use for children. -

end snip

NP Savely knows a bit about the CD57 since she once shared an office with the originator  of that test--- Dr. Stricker. She also wrote an article about it that was printed in the (gasp)--- Public Health Alert rag.

She 'waffled' a bit about it also later on.

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Good luck with your bicillin LA shots. They were what gave me a fairly long lasting remission.