Hello Dear,
Connective tissue diseases are chronic inflammatory autoimmune disorders which can affect all connective tissues, i.e. joints, skin, muscles and blood vessels, and therefore have multiple effects on many different organs throughout the body. Although the commonest one is rheumatoid arthritis.
Osteoporesis is not a connective tissue disorder,it may accompany a connective tissue disor
Refer http://www.arc.org.uk/arthinfo/medpubs/6529/6529.aspder.
Best
thanks . as you know having chiari malformation and syringomyelia , connective tissue disoders such as EDs is well known