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Atypical cells in an ovarian cyst
My mother was diagnosed with breast cancer in 2008. She had a lumpectomy, (3 lymph nodes were taken out, but only one of them were positive) chemotherapy and then radiation. The tumor had both estrogen and progesteron receptors, but no HER2 receptors. Therefore, she gets hormone treatment. She started to take tamoxifen in last September. (The US before the treatment didn't show anything in the ovaries.) At the end of September, she had other examinations (as tamoxifen reduce the risk of breast cancer, but it increases the risk of uterine cancer and so forth..) The US examination showed something in her right ovary. Then there was an MR examination. The result was: Atypical ovarian cyst, it is needed to be controlled. The cyst mainly contains fluid, but it has a soft / semi-solid part. Since September, she has had more examinations in order to monitor the cyst and make sure that nothing has changed. Fortunately, nothing has changed since September, so it didn't get larger, it didn't change in look, it didn't grow, it's the same. However, my mum's oncologyst still worries, because of the semi-solid part. A very experinced gyncologist examined my mum, he took a look on the cyst, but he couldn't decide wether it is malignant or benign. He told my mum that only surgery and biopsy can decide it. Nobody had ovarian cancer in our family, even not breast cancer. We are still worried. My mother'll have a surgery in April. (Her ovaries will be taken out)
Is an atypical ovarian cyst malignant (if it didn't change)? Can it be benign (if if didn't grow) ? Can tamoxifen cause such a cyst?
Is an atypical ovarian cyst malignant (if it didn't change)? Can it be benign (if if didn't grow) ? Can tamoxifen cause such a cyst?
Sorry, but I do not have the answers. A cancer doctor would be the one to ask. Maybe ask this on the expert forum....or ask the ladies on the ovarian cancer forum.
Is every progesteron and ostrogen positive breast cancer related to BRCA gene mutation?
It is possible, but blaming genes is pointless. It is more important to treat something that is not right.
Yes, I heard that it's hard to decide whether a cyst is benign or not (only removal can help). I read an article about BRCA gene mutation. Can it be a possibility? Nobody died of ovarian and breast cancer in our family. (none of my mum's grandparents and greatgrandparents died of cancer.)
Even doctors don't know without surgical removal of a cyst and pathology. If in doubt, take it out. This is the approach your doctors need to take.
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