Thank you for your response, MM. I will stop taking the Vagifem until I talk to my doctor. Actually, I'm also waiting for the results of a BRACAnalysis, so she may even suggest I stop until I get those results. Thanks again.
My doctor didn't think it mattered much if I continued using Estrogen creams or not. It's not the same format as Vagifem, but same general idea.
I had just started using the cream, in fact, and the tiniest quantity, and then when the U/S results came back, I had serious second thoughts. My doctor said not much is absorbed in the system, but if you feel breast tenderness, then some system absorption is taking place. All the same, I freaked out enough that I stopped creams when my cyst was found. My gyn did encourage me to go back to them once my ovaries were removed (along with my natural "estrogen factory"), mainly as an external topical treament where system absorption is highly unlikely. Even my gyn uses it that way for herself!
If it worries you, quit it for awhile. You can always go back to it when you know more about what you have and what the doctor recommends. That cyst is really small but post menopausal ones always raise some alarm because it makes no sense why they would occur.