Why are you asking?
It depends on what your taking and how long you have been on the medication.
There are many different variables.
I f you can tell us which opiate your talking about i may be of more assistance.
i recentley went to pain mangement and they did a uds i had a follow up visit 2 weeks later and she said i had on oxycodone in my system and that she had to retest me, and ordered a uds can someone tell me what they are checking for? if i took 2extra pills the day before can they tell?