How to treat schizophrenia after autism, epidermal nevus, sarcoidosis

[peg106]

My son was born with what was diagnosed as an epidermal nevus.  It stretched from his left nipple to about his left shoulder blade, was about ½ inch wide when he was a baby, and was textured and raised.  It was surgically removed when he was 2 years old because he scratched it excessively in the summer when he perspired.  He also had a congenital cataract (posterior lentiglobus) in his right eye.  At age 6 he was diagnosed with Pervasive Developmental Disorder (on the autism spectrum) with severe language disorder.  Despite all this, with the help of rigorous speech/language and psychological therapy, he excelled in school and college.  Unfortunately at age 23 he developed schizophrenia (delusions and hearing voices) which has been resistant to numerous antipsychotic medications for 3 years.  It is heartbreaking to see him nonfunctioning after having overcome so many challenges. Recently he was also diagnosed with sarcoidosis, from a rash on his legs. My question is, is this cluster of symptoms what you would find in epidermal nevus syndrome?  And most importantly, is there any treatment you would suggest for the schizophrenia, given the rest of his medical history?

[DonFairley777]

Hi Don fairley, here any successs with treatments

[Dmeal]

"Abstract
A case is described of a 40-year-old man who developed sarcoidosis and at the same time malignant change in a congenital pigmented naevus of his foot. It is proposed that the sarcoidosis may have acted as a predisposing cause of the melanoma in this case. The difficulties of diagnosis and management of patients with coexistent malignant melanoma and sarcoidosis are discussed."
Patterns of disease -
sarcoidosis -  lymphoma syndrome
mycosis fungoides - melanoma syndrome
sarcoidosis - schizophrenia - myasthenia gravis syndrome
mycosis fungoides - HTLV proviral DNA and borrelia
"From nevus to mycosis fungoides to sarcoma"
HTLV-1 proviral DNA microdeletion in the genome
borrelia plasmids in the genome
viruses mutate
spirochetes mutate

[maatson]

The International Journal of Psychiatry in Medicine  
   Issue:   Volume 22, Number 3 / 1992  
   Pages:   269 - 274  
   URL:   Linking Options  

'Neurosarcoidosis Presenting as Schizophreniform Disorder'.- This patient responded wellto steroid therapy and his mental symptoms disappeared.

[Dmeal]

Dear Peg,

My family hx is very similar to your son's symptoms. I have a family hx of mycosis fungoides, nevus, autism, aspergers, schizophrenia, sarcoma and sarcoidosis. The two common denominators in all of these diseases are the spirochete borrelia and the proviral DNA of HTLV-1. So, very soon somebody in the scientific community is going to determine if all of these diseases are due to an ancestral infection with borrelia integrated in the DNA, or HTLV-1 proviral DNA integrated into the DNA. Also, some non-blodd relatives are sick with leiomyosarcoma, ALS, so whatever the agent is, it is also transmissible, and possibly even from saliva according to Morozov researching mycosis fungoides in European Russia. So, trichosanthes kirilowii should help with the virus, Noni with the borrelia and l-carnitine with the methylation.

Best wishes,
Dan.

[rumpled]

I did some research and sarcoidosis and schizophrenia were not on the list of the many things that can happen with the plaques, so I would question the diagnosis myself.