Elevated calcium, Low Vitamin D, normal PTH

[Kelly5858]

I'm 51 y.o. white female

Blood test 4/9/10 revealed:

Calcium 10.6
Vitamin D, 25-Hydroxy 28.9
Creatinine 1.04 H
eGFR 56

Blood test 4/16/10 per phone call w/nurse

Calcium 10.1
Ionized calcium 5
PTH 34

Medical History

Crohn's disease (remission since hemicolectomy 12 years ago)

Hashimoto's (both thyroid lobes removed 2001 & 2007 due to adenomas).
Thyroid bloodwork normal (T4 1.46; TSH 4.070) - take .150mcg Synthroid daily

Bone scan 1/09 showed osteopenia left hip.

My GYN just started me on 50000 units of Vitamin D weekly.  

I have copies of 10 years of BT results and my calcium has almost always been around 8.9 - 9.1.

Is this the appropriate course of action at this point?

[foreverlostmom]

My calcium started at 8.9 and raised to 10.1 over a few months with 2 tests staying above 10 and my vitamin D at 39 normal PTH.  I was worried about taking vitamin D but my calicum did not raise with it.

I also have hashimotos

[Kelly5858]

Nothing has been said about my eGFR.  It was 59 last year and nothing was said about it.  The range on my labwork shows the calcium range at 8.7-10.2 so the 2nd one is back in the normal range.  I have no idea what caused my elevated calcium but I've read that it is not normal for it to change much over a lifetime unless something is out of whack.  It's usually around 8.9.  I've also read that high calcium will often go back to normal and back high.  I'm just wondering if the vitamin D will make it go back up.  

Thanks for taking the time to write me!

[LivingInHope]

First off, did the doctor say nothing about your eGFR or estimated glomerular filtration rate which tells how well your kidneys are working?  Because according to the national kidney foundation, the average number for your age category is 93.  On table 5, they list your number of GFR as being ins stage three kidney disease, where the doctor should be evaluating and treating complications.  It looks like your second calcium test got into normal range- am I right?  

  If your calcium is high 2 out of 3 lab samplings, A Manual of Laboratory Diagnostic Tests, 2nd edition (old book) by Frances Fischbach, says that establishes hypercalcemia.  They say hypercalcemia's "greatest clinical importance rests in its association with cancer, including multiple myeloma, parathyroid tumors, nonendocrine tumors producing a parathyorid-like substance, and cancers metastasizing to the bone".

Lab tests online lists some other reasons (besides hyperparathyroidism and hyperthyroidism and cancer) for hypercalcemia, including sarcoidosis, TB, being immobilized for a long time, taking too much vitamin D and kidney transplant.