FT3 high end of range?

[thyroidleaner]

Hey everyone, so been having some symptoms of hyper (constant hunger, sweating, ect).

First set of labs.

TSH 1.45
T4 7.1
T3 Uptake 39%

Second set of labs.

TSH 1.2 (0.38-5.5) mU/L
T4 Free 16.9 (10.5-20.0) pmol/L
T3 Free 6.1 (3.5-6.5) pmol/L
Thyroperoxidase Ab 13 (<35) IU/mL

Should I further run any other tests (TSI)? Or am I basically not looking at a thyroid problem anymore..

Thanks so much.
thyroidleaner

[thyroidleaner]

Hey Barb,

Got some updated antibodies lab. Confused on what to do at this point, and if I should be worried.

TSI was 25% (<139% ref)
TgAb was <20 (20-40 ref)

Would appreciate any input! Thanks.

[Barb135]

I'm familiar with ZRT lab, but not the iodine.  I do know that some doctors don't give credence to spot tests, so you might want to check into that, before having the test done.  As for usefulness, I'm not sure about that either.

It seems that the antibody tests would be more useful.

Your original post said you were having symptoms of hyper and your high FT3 and FT4 would bear that out.  Remember, while Hashi is most often associated with hypo, there are often periods of hyper.  Symptoms can also "cross over" between hyper and hypo; it's also possible for symptoms to be present long before blood work shows a problem.  Keep in mind, also, that  typical symptoms of a thyroid condition can also apply to other conditions.

Have you had a thyroid ultra sound to confirm that you don't have a goiter and/or nodules?  I was told I didn't have a goiter or nodules either, at first, but ultra sound proved that wrong.

If all antibody tests are negative, you may want to research your symptoms again and determine to which other conditions they may apply.

[thyroidleaner]

Sorry Barb, I meant to say high 96s not high 97s.

It's very interesting and hopefully more tests will reveal further. Do you know about the ZRT lab testing for iodine with urine spot test. It only requires one urine sample from the night before bed and one in the morning, no loading required. Do you know if that would be useful accurate?

[Barb135]

Some would say, that because of your "lower than normal" body temp, you would be hypo.  You could be, but body temperature an fluctuate, too.  Mine is hardly ever 98.6, on the dot, but that doesn't mean there's something wrong..... even though that's the "normal" temp.  I've read that "normal" can range from 96 - 100. Like everything else, we are all different and body temp won't be the same for all of us, nor will it always be the same in any one individual.  

Morning temperatures are more important in determining hypo, but even that should be taken with a grain of salt, because of the fluctuation from person to person.

[thyroidleaner]

Thanks for the response Barb,

I also forgot to mention my body temperatures are around high 97.0 in the morning and near dinner time it gets up to around 98.0. Any idea how this would potentially play into the picture?

[Barb135]

TSH is a pituitary hormone and changes wildly, even intraday.  It's not indicative of actual thyroid function, even though doctors use it for that.  You have to look at the FT3, FT4, antibodies, and most importantly -- symptoms.

Not everyone with Hashi's has a goiter .........depends a lot on whether or not the antibodies are raging or not...... I have a multinodular goiter, but after 4 years of treatment, the "goiter" part is now minimal, because the swelling/inflammation has gone down.

You could be in a hyper phase of Hashi's or you could have Graves.

[thyroidleaner]

Thanks Barb,

I was wondering is it somewhat rare to have no goiter and Hashi's? Does the change from 2.4 to 1.2 look like something you might see with Hashi's?

[Barb135]

Either, or both, TPOab and TGab, can be present with Hashimoto's.  Even if you tested negative for TPOab, you could still have Hashi, if you have the TGab.  

There's also a small portion of people that have Hashimoto's, but test negative for antibodies.

TSI is the definitive test to confirm/rule out Graves Disease.  TSI is not present in Hashimoto's; however, very rarely, we see members who have both Hashimoto's and Graves.

[thyroidleaner]

Barb,

I was tested for TPOAb, is that the same as anti-TPO? Is the other test I am looking to take thyroglobulin antibodies (TgAb)? And TSI? Do you think Hashi's is possible? I have no goiter or thyroid pain.

Thanks!

[Barb135]

Yes, Hashi is possible, even with normal TPOab.  Did you have a TGab, as well?  Both TPOab and TGab diagnose Hashi.  Some people have one or the other antibody, some have both.  So even if you are negative for TPOab, you could still have TGab.  Then there is a very small percentage with Hashi, that test negative for both.

Since your levels are high, be sure to get the TSI.

[thyroidleaner]

Would Hashi's be possible even with the TPO Ab normal? I'll look into the TSI for sure.

[Barb135]

FT3 and FT4 are both high in ranges - might want to do antibody tests for both Hashimoto's, which can present with periods of hyper and Graves.

Hashi antibodies are TPOab and TGab.  Graves is TSI.