Help reading labs please!! Graves' disease

[BpaL11]

I just received my lab work and I need help.

Tsh 7.420 (.45-4.500)

T3 3.4 (2.3-5.0)
T4 1.42 (.93-1.60)

This is the confusing part. I had my antibodies tested because my levels have been rapidly going hypo.

Tsh receptor antibody:    .8

Reference range:
Antibody titer:
1.5 u/l = positive

I don't really understand what's going on. I'm on 2.5 mg of methimazole daily. If anyone could help it would be greatly appreciated!

[BpaL11]

Okay thank you! I have been weaning rapidly and I was on 15 Mgs about a month ago, but even as I dropped the dosage my tsh still continued to rise so I think it might be time to get off the stuff. Thank you for your reply

[goolarra]

Usually, that much of a change in TRab indicates remission.  You still have some TRab, but you're now in reference range.  TSI (thyroid stimulating immunoglobulin) is a better test than TRab.  TRab (TSH receptor antibodies) include several subtypes:  blocking, binding and stimulating.  Blocking and binding antibodies have the opposite effect of the stimulating antibodies.  What's important with regards to Graves' is the stimulating antibodies, and the TSI test counts them separately from the others.  

Do you still need to be on methimazole?  Your FT4 is a little on the high side still.  However, FT3 looks really good.  TSH is high, which indicates your pituitary thinks your levels are too low.  I'd certainly want to talk to my doctor about discontinuing meds at this point.    

[BpaL11]

I believe I was diagnosed with graves based on my symptoms and on the positive trab antibody results which were up around 3.45 u/l in December... If it's negative now do I still need to be on methimizole? Am I technically in remission? And i do feel pretty sluggish lately and everything looks unreal to me.... I'm guessing these are hypo symptoms?

[goolarra]

Your T4 is still pretty high in the range; it's 73% of range.  The guideline is around 50%.

However, your FT3 is not too high at all.  It's 41% of range, which many would find too low.  (Guideline here is upper half to upper third of range.)

TSH, for what it's worth, indicates you are hypo.  

So, your TRab is basically negative.  Did your doctor test TSI?  On what basis were you diagnosed with Graves'?

How are you feeling?  Have your hyper symptoms resolved?  Are you now having hypo symptoms?