compounds

[Brucergoldberg]

Is anyone here on a compound?  If so, what is in your compound?   is it one pill or two?   what is your decision to do a compound?   I am on 2.75 grains of armour and every time i dose the t3 hits me like a ton of bricks.  I have been on this for 7 months now.  I have no body pain, I'm not tired, the only symptoms i have are the anxiety attack every day after i take my meds (which they said is either from the t3 or from me converting too fast)  and the ear ringing.  SO what they are planning is a synthetic compound close to 2.75 grains armour (as a synthetic) with 1/2 as much t3 added.    Any thoughts, hate mails, ideas etc?

[Brucergoldberg]

correct.    the prescription i have right now is very very close to yours payton382.  It is 100 of t4  and 15 of t3.  I personally believe it is still too much t3.  I am a little frustrated because i told the dr. I didnt want a lot of t3 in my prescription because on all of my tests my t3 is very high and my t4 is very low.   I would like to have a high t4 and a high t3  but i don't want it to be disproportionate.  

Payton382-     How are you doing on that slow release stuff?   Everyone told me not to get the slow release, but the compounding pharmacy made it as a slow release anyway.   Also , what were you on prior to the compound and do you feel better, worse or indifferent?

I will start this on Monday.  My wife will be at work and the kids will be at daycare so if for some reason this medication does not agree with me, they ill not be here while i go through my day.

[Barb135]

The "side" was simply a figure of speech.....didn't mean to confuse anyone. When you have the compounded, or the desiccated, you have both the T3 and T4 in the same capsule/pill. I'm talking about taking them separately.

The T4 is one pill, the T3 is another, and taken separately, as/if needed.  For instance, I take 88 mcg Tirosint, which is my T4 med that I take first thing in the morning; after an hour or so, I add a small dose of generic T3 in a separate pill, and which I can split into multiple doses during the day - 5 mcg in the morning, and 2.5 mcg around noon.  

For me, keeping the 2 separate has been easy, because I can control them independently, without having to have a whole new compound, each time I need a small change.  I've tweaked my dose, by alternating different dosages of T4 med and I've added/subtracted the dosage of T3.

In Bruce's case, he's been on the desiccated, but it seems that the T3 is too much; he hasn't tried a T4 only med since his TT; therefore, if he went to a T4 med and found that he really does need a small dose of T3, he can just add it.

[payton382]

Bruce,

I currently take a compound of T4/T3 at 120/10 with sustained release so the T3 releases slowly over 12 hours.  I only dose one capsule once per day.

I went compounded after trying T4 only, desiccated, and desiccated with T4.  

Still trying to tweak, based on labs and symptoms to find optimal compounded dose.  The 120/10 is a brand new script so not sure if this'll do the trick yet.  
  

Barb,
When you said "Why not just go with a synthetic T4 and add a T3 "side" to it?"  What do you mean by that?  

Is there a difference between taking a compounded T4/T3 versus "synthetic T4 and adding T3 to the side"?  Sorry, if that's a stupid question but I'm wondering if I cannot eventually get symptom relief (hoping this new, latest dose will work) if there's an advantage to splitting the pills up?  Would love to hear your thoughts.

Sorry, Bruce don't mean to hijack your post....  Just curious.      

[Barb135]

No play on words - I took what you said literally. Why would you trust the pharmacy and not the med?   Now I understand that you're afraid of it; that's different.

Why not try going back to a T4 and forget about the T3 unless/until you find that you really need it?

Face it - combos, either desiccated or compounded, are not right for everyone, so maybe you need to lose that idea.  Just a thought.

[Brucergoldberg]

Ithank you for your support.  Why do you always have to play on my words?   My heart races, I'm agitated , I have horrible stomache aches, my ears ring, my hands shake, I feel too dizzy for sex, I can't sleep, my throat hurts .    I am just worried that despite the medicine being exact, it may be another failure for me and I've been on erfra for 7 mos.

[Barb135]

Bruce, that makes no sense --

"i have full faith in this pharmacy.   I do not have faith in the medication i bought from them."

Why on earth would you have faith in the pharmacy, but not the medication you got from them?  That's just plain silly.

You're obsessed with your thyroid issues - there IS life beyond thyroid - you need to find it.

[Brucergoldberg]

i have full faith in this pharmacy.   I do not have faith in the medication i bought from them.

[sunrock]

What happened to me with the compound capsules, was the pharmacy I got it from was hand filling it.

I started to notice that the some capsules were full and other not as full.

They also used a filler with a time released jell that may have given me some problems.

Not sure if it is just this pharmacy.... some things to ask about are
what fillers do you use? any reported problems? How do you fill the caps? etc

good luck

[Brucergoldberg]

The compound is going to be .50/7.5    so total for the day will be 100/15  which is almost 1/2 the t3 in the erfa I'm taking.

latest labs:

ft3   4.2      2.3  to 4.2
Ft4  1.0       .9   to 1.8
Tsh .61     .40 to 4.5

my biggest problem is that i take my erfa and 4 hours later my ears get clogged up, start to ring and i get horrible anxiety -  too much t3 at once, or am i converting the t4 too fast?  if i am converting too fast, is there anything i can do?

[Barb135]

Why not just go with a synthetic T4 and add a T3 "side" to it?  Works for me, as well as a lot of others. Or maybe you don't even need extra T3, is you're converting okay.

[Jackie419]

P.S.
I was on 3 grains compounded with ratios that matched Armour, with an olive oil filler. I took it in 2 doses per day. I ended up not staying on it as it was too hard to tweak the dosage as it was in capsule form-( I am now on 3 1/4 to 3 1/2 grains of NP Thyroid per day). Otherwise, it was quite a bit more expensive but sounds like you may need to go that route.

[Jackie419]

Why do synthetic when a compounding pharmacy can fix you right up with the right ratio of t3- t4 in dessicated form? I am sure someone has asked you this, but do you ever split your doses? The compounders I used were great and spoke to me any time I had questions and worked with me and the doctor I had. I personally would not mess with synthetic, but that's me. Good luck whatever you decide, i know this has been a long road for you. A long road for us all.