Looking for any help or answers

[answersplz9]

Any feedback or help would be awesome....2 years ago I woke up and my eyes were almost swollen and I had a rash.  I went to prompt care and they gave me prednisone.  In the last 2 years the short version I have had a full allergy test, i have had multiple flair ups more than I can count and had to be put on prednisone again.  Here are my symptoms more frequent, weigh gain, swollen feet and hands, tired for no reason, headaches, stiffness or muscle aches, could say depressed because I'm tired of not feeling like myself, vision has noticed a difference as well as when it flairs up bad, nausea, vomiting, itching, rash on neck and chest, queasy, fuzzy thinking....My allergist put me on Zolair shots I have still had outbreaks....in the last 2 months they found out I have an autoimmune disorder and I have had full lab works done on my thyroid but they say it all looks mostly normal....I am trying to get into and endocrinologist but can't be seen till December.  That is a long way...I have done some reading on Hashimoto's or Graves Disease and the symptoms seem close but not sure my tests are saying it sooo just trying to reach out.  

[gimel]

You have a number of symptoms that can be related to hypothyroidism, but the tests done so far are not adequate for that diagnosis.  As Red Star pointed out the hereditary angioedema suggests that you may have either/or Thyroglobulin or Thyroid Peroxidase antibodies, indicative of Hashimoto's Thyroiditis; however, your TSH doesn't strongly indicate Hashi's.   Also, your other thyroid tests are somewhat outdated and not nearly as revealing as would be tests for Free T4 and Free T3.  

So I do suggest that you should go back and request to be tested for Free T4, Free T3, TPO ab and TG ab.  I also suggest tests for Vitamin D, B12 and ferritin.  It may well be that more than one ailment is involved, but I suggest doing these tests first, so that we can better evaluate your status.  

[Red_Star]

Did your doctor test your thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb)?  Here is a study on hereditary angioedema and these thyroid antibodies (thyroid microsomal antibodies is another term for TPOAb).

"Sera from 91 patients with hereditary angioedema were screened for thyroid antibodies. The results for the 77 patients more than 17 years old were compared with previously published data for the prevalence of thyroid disease in a large community (Whickham). Of the female patients with hereditary angioedema, the prevalence of thyroglobulin antibodies (TGA) was 14.0%, higher than the expected 3% (p less than 0.001). The prevalence of thyroid microsomal antibodies (TMA) was 20%, also higher than the expected 7.6% (p less than 0.01)."

Hereditary angioedema and thyroid autoimmunity. J Clin Pathol. 1987 May; 40(5): 518–523.

[answersplz9]

tsh 2.51  (.450-4.500)
Thyroxine (T4) 10.0  (4.5-12.0)
T3 Uptake 22  (24-39)
Free Thyroxine Index 2.2(1.2-4.9)
Trilodothyronine (T3) 136  (71-180)

Hereditary Angiodema (HAE)  37  (9-36)
Complement C4 Serum

Thyrotropin Receptor Ab, Serum <.51 (.00-1.75)
Thyroid Stim Immunoglobulin 21 (0-139)
Thyroxine Binding Globulin 22 (13-39)

Let me know if you need other tests

[gimel]

Please post your thyroid test results and reference ranges shown on the lab report.