Pituitary, Hypo, Hyper or anything?

[Blue727]

Can you please look at these and tell me what you think?  I have a ton of hypo symptoms, but have both anxiety and depression.  My results are usually "normal" in range, but are always at the bottom of that "normal" range.  Does it sound like pituitary, hypo, hyper or anything like that based on these results over the years.  Your help is greatly appreciated.  Thanks!

Results: Ranges:

10/12/05:

TSH: 1.20 0.40 - 5.5 MU/L

2/21/06:

Free T4: 0.91 0.59 - 1.17 ng/dL
TSH: 0.94 0.35 - 4.82 uIU/mL
T-4, Total: 6.4 4.5 - 12.0 MCG/DL
T-3 Uptake:34.6 25.0 - 35.0% Uptake

8/15/06:

TSH: 1.11 .34 - 4.82 uIU/mL

10/12/06:
TSH: 1.20 0.40 - 5.5 MU/L

6/21/07:

T-3, Free: 377 230 - 420 PG/DL
T3, Reverse:0.19 0.11 - 0.32 ng/mL
Free T4: 0.73 0.71 - 1.85 NG/DL
TSH: 1.39 0.50 - 5.00 uIU/ML

7/17/07:
Here are the saliva test results;

fTSH 57 Normal
fT4 0.25 Normal Normal: 0.17-0.42 ng/dl
fT3 0.27 Borderline Low 0.21-0.27
TPO Positive
E2 (Estradiol) 9 Male (20-49 yrs): 1-3 pg/ml, Male (50-85 yrs): 1-5 pg/ml
P1 (Progesterone) 30 Male (adult): 5-95 pg/ml
TTF (Free Testosterone) 34 Male (20-30 yrs): 60-110 pg/ml

Cortisol:

7:00-8:00 a.m. 6 Depressed 13-24 nM
11:00-Noon 4 Depressed 5-10 nM
4:00-5:00 p.m. 3 Normal 3-8 nM
11:00-Midnight 5 Elevated 1-4 nM
Cortisol Burden 18 23-42

DHEA: 4 Normal 3-10 ng/ml

My morning Cortisol blood test was 19.3 (Range: 4-22 MCG/DL). Antibodies test was negative.

8/7/07:
TSH: 1.80 0.50 - 5.00 uIU/mL

9/12/07:

Free T4: 0.75 0.71 - 1.85 NG/DL
TSH: 1.27 0.50 - 5.00 uIU/ML

1/19/08:

Free T4: 0.66 0.71 - 1.85 NG/DL
TSH: 0.17 0.50 - 5.00 uIU/mL

1/30/08:

TSH: 0.95 Range: 0.50 - 5.00 uIU/mL

Estradiol, Serum <32

Estradiol Reference Ranges:
Male: <=54

It goes on to say no pediatric reference range established.

T-3 Uptake: 40.31 High Range: 25.0 - 35.0% Uptake

T-4, Total: 5.7 Range: 4.5 - 12.0 MCG/DL

Free Thyroxine Index: 2.30 Range: 1.12 - 4.20

T-3, Total: 93 Range 60 - 181 NG/DL

Testosterone, Total: 393 Range: 241 - 827 NG/DL

[AR-10]

Your T4 is always on the low end, even when your TSH is low.
When yout TSH dropped to hyper, your T4 dropped below range. It should have gone up, not down.

But even though you have a low/normal T4, you seem to have plenty of T3 in June. The T3 should have been lower.

The whole thing is puzzling.

It sounds like maybe it is a pituitary problem.

You're getting a normal TSH with a low T4. your TSH should be running higher.

That's just a guess.

Have you tried asking Dr. Lupo on the other thyroid forum? He answers questions over there. You may have to try several times to get your question posted. They have a limit of so many per day.

http://www.medhelp.org/forums/show/120

Try asking over there, and keep an eye on both threads(posts).
Good luck. Hope you get an answer that helps.

[Blue727]

Can anybody help me understand this stuff and if there is a potential issue?  Thanks!