Diet pop is ALL I drink....(Diet Coke)
Literally...
You can take it at whatever time works best for you, but, yes, it is important to take it on an empty stomach...no food or drink for 3-4 hours prior to meds and none after for 0.5-1.0 hours. I responded on another of your threads...we'd have to see your labs before responding on your T3 question. Diet pop isn't great for you, whether it affects your meds or not. Have you considered to switching to a non-sweetened, flavored sparkling water?