Hi
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I am not sure what you mean by elevated liver levels. Many a times AST (SGOT) and ALT OR SGPT (both are collectively called transaminases) rise without any cause. Because AST is found in many other organs besides the liver, including the kidneys, the muscles, and the heart, having a high level of AST does not always (but often does) indicate that there is a liver problem. For example, even vigorous exercise may elevate AST levels in the body. However to reach at that conclusion the medical causes of these raised transaminases have to be ruled out. Causes of liver transaminase elevations include viral hepatitis, alcohol use, medication use, steatosis or steatohepatitis, and cirrhosis. Steatosis and cirrhosis are ruled out by the ultrasound. Other common health conditions, such as diabetes, heart disease, pancreatitis, hemolytic anemia and thyroid disease, can also cause liver transaminase elevations. Most liver diseases are characterized by greater ALT elevations than AST elevations except cirrohsis and alcohol abuse. ALT also rises in bile duct obstruction due to stone.
Raised alkaline phosphatase (The normal range is 44 to 147 IU/L (international units per liter).is often found in a growing child and at puberty. There are several bone disorders too that can raise this enzyme like rickets, osteomalacia, Paget’s disease of the bone, tumors, metastasis and recent fracture. An elevation in AP is often seen in cholestatic liver disease, pregnancy, bone disease, and occasionally with inflammatory bowel disease. In an otherwise healthy individual a rasied AP could be due to false positive test and the test should be repeated. If it is still high then other mentioned causes should be ruled out.
High concentrations of GGT are found in the liver, bile ducts, and the kidney. Hence kidney and urinary problems could be causing the high GGT level. Greater-than-normal levels of GGT may indicate: congestive heart failure , cholestasis (congestion of the bile ducts) , cirrhosis, hepatitis , liver ischemia (blood flow deficiency), liver necrosis, liver tumor, high alcohol intake, use of hepatotoxic drugs (drugs toxic to liver). The good results will start appearing within 24 hours of stopping alcohol but will be very minimal. It takes about a month for the levels of GGT to come down to near normal value provided you abstain from alcohol during this period.
Depending on which enzyme levels are raised, see if the causes for the same have been ruled out. Since you have spleen involvement, enlarged nodes and anemia, hemolytic anemia should be ruled out. I feel you should consult a hematologist and a hepatologist. Take care!
If you don't get better you should look into lyme disease. Lyme disease is the route cause for autoimmune conditions, fibromyalgia and CFS. It can also cause all of those symptoms you have. If you decide to go this route then you should look for a lyme specialist and get tested through a certain lab. My lyme doctor saved my life, my husband's and my son's after years of suffering with this terrible disease. When you have lyme disease you can get many different kind of infections from just one tick bite and you don't have to have a rash. We have babesia, bartonella and borrelia infections that we are currently fighting.
It ended up being Cytomegalovirus! Who would've thought?!?
Hello,please have your physician check for lupus do a FANA also, have your thyroid tested for a autoimmune disorder -hashimoto's disease with malignant or nonmalignant nodules. Good luck~blessings~feel better soon Audrey !