Is there anything that can cause medications to suddenly have an increased effect on someone? like both good and bad effects? and like All medications? I have hyperesthesia and OCD, and I recently had to lower all the medications I take to practically nothing and it feels exactly the same as when I used to take higher dosages. Then recently I got my first corazone shot and it was so overwhelming that I fainted almost seconds after getting it and was stuck twitching on the floor for fifteen minutes and barley able to move. apparently one of the doctors first female patients to faint from such a thing. Things like this didn't have such a pronounced effect even as short as two years ago. Is this something I should be worried about, or is it normal for someone approaching 25 years old?