Hi Dr,
If a male with PSA in the range of 1.4 in later 40s and early 50s, last year tested in this range was about 18 Mo ago. Recent test was about 2.6, with normal DRE and enlarged prostate (not actual prostate density test though).
Is this situation concerned? Need biopsy? And with PSA<4, fPSA cannot help to distinguish if cancer related, what test you may recommend if it is your patient?
The Dr order him a course of antibiotics, but just the first time with medicine, feel very bad headache, is that normal, should continue to take the medicine?
Thank you in advance for your advice and help!
Hi
PSA is prostate specific antigen .At this point however, it has been shown that PSA is not really specific. Liver problems and even benign enlargement of the prostate may increase PSA levels. Breast and ovarian diseases have been shown to affect PSA levels in women.
In your case you are thinking of a kidney infection. If the infection affects the prostate then PSA level may be increased. In your case, a prostate infection or inflammation has to be ruled out. Your PSA is not highly elevated and this may be monitored again after a few months .It is not really the current level of PSA which matters but the pattern or trend of increase which may need close assessment.