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Methotrexate, ectopic pregnancy and bleeding

I have had two doses of Methotrexate administered by a needle. Between doses, the embryo grew from 2.8 cm to 5.8 cm in a span of a week. My Bhcg went from 2600 down to a little over 900. Was at the hospital under observation but have been released. This is my first night home, and I am concerned about what can happen. Experienced a fainting spell while under observation, low blood pressure after, but since then went up. Still ight headed, bleeding light to moderate, bright red, no tissue or clots. Slight cramping in my left side (where ectopic was discovered). Does anyone have any similar experiences or experienced this? What was the outcome? Am I just paranoid, or am I in grave danger at this point? ALL honesty is respected, will not get offended. Thank you
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Avatar universal
I don't know much about ectopic pregnancies, but I wanted to say how sorry I am! I do know that they can be very dangerous and if you feel like you are experiancing things that you shouldn't then go to the Dr. or at least call. I know it's not something you want to mess around with. If you feel something is wrong then call. Or maybe try googling it and see what the normal symptoms are that you should be having. Again I'm sorry that you lost the baby! You will get a lot of support on this forum from these women here if you need it.
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Avatar universal
I am so sorry for what you are going through.

I had a Metho shot in August for "presumed" ectopic. but only had one and was sent home that day.

Your body seems to be reacting differently...as all of ours do. I hope it is all over  for you soon.(so your body can get back to normal)
You will be in my thoughts and prayers.

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Avatar universal
Is There Anything Else I Need to Know?

The following points are important:

Avoid alcohol and vitamin preparations containing folic acid until the hormone level is back to zero.
Avoid aspirin or drugs such as ibuprofen for one week after treatment. It is fine to use regular paracetamol (to a maximum of 2 tablets, 4 times per day)
If you have severe pain or heavy vaginal bleeding, get in touch with your doctor.
It is important that you use adequate contraception for 3 months after a single injection or six months after more than one treatment.
Be sure that all of your questions have been answered.



What are the possible side effects of methotrexate?
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Avatar universal
I had one shot of methotrexate Oct. 20/06 and my HCG levels were fluctatiing all over the place. My Dr. thought I needed another shot of methotrexate but then my levels went to 25, which is good. The bad thing is, is that I'm still bleeding. I've been bleeding for just over 6 weeks now. It sucks. The Dr.'s don't seem too concerned about it though.
I hope you are doing okay and remember just call your doctor or go to the ER if you feel worse.

I'm sorry for what you are going through.
From your Canadian buddy
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165701 tn?1342627584
I too had to have two doses of methotrexate before my numbers started to go down. It still took about 3 weeks of havimg my blood checked every two days after the second shot.  One night i had extreme pain and the next morning i went to urinate and what i assumed was a blood clot the size of my fist(it was actuall the sac)came out. Afterwards I was fine.
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150483 tn?1212168556
Hi,I'm sorry about your ectopic.I had one on 8/25.I was given 3 shots,first 1 one did'nt take levels did'nt go down for 1 wk.And was given two more with vitamin shot in between.After exactly 1 wk. I started to bleed ALOT.Cramping & clotting that lasted 3 days.Then 1 wk. later I bled again for 1 month levels didn't go down for almost a mon.After levels went down to zero, 3 wks later I got AF on 10/06.Then again on 11/01.This is my 2nd cycle since.I was told NOT to take folic until levels went down comm.After I have taken prenatals & xtra folic & wil wait till jan to ttc.I know this is hard & scary but it will get better.Ask alot of ?'s.And were here for whatever.Good kuck ....nanis
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150483 tn?1212168556
Hi,I'm sorry about your ectopic.I had one on 8/25.I was given 3 shots,first 1 one did'nt take levels did'nt go down for 1 wk.And was given two more with vitamin shot in between.After exactly 1 wk. I started to bleed ALOT.Cramping & clotting that lasted 3 days.Then 1 wk. later I bled again for 1 month levels didn't go down for almost a mon.After levels went down to zero, 3 wks later I got AF on 10/06.Then again on 11/01.This is my 2nd cycle since.I was told NOT to take folic until levels went down comm.After I have taken prenatals & xtra folic & wil wait till jan to ttc.I know this is hard & scary but it will get better.Ask alot of ?'s.And were here for whatever.Good luck ....nanis
Helpful - 0
126702 tn?1240888250
Hi There

SO sorry for your loss. I had one shot  of methotrexate only and the thing i remember the most was how truamatic and painful the bleeding was. I think the cramping was underestimated! I did bleed very heavily for a week and a half.  My levels also went down to zero in 2 weeks. I too will be TTC in Jan like nanis.

I hope you feel better soon.

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Avatar universal
I'm so sorry your going through this. I went through this myself and was pretty traumatized after the ordeal.I'm on my eight'th pregnancy right now with only 2 live children. The rest were miscarriges including one ectopic tubal pregnancy. I expierenced the same symtoms. With my ectopic ordeal I knew I was miscarring at 6 weeks but I was in denial because I've been trying to get pregnant for about a year and was hoping that my cramping and brown spotting would disapear. And then while at work ( I'm a caregiver at a nursing home) I was on my way to my next client to get him ready for breakfast and housekeeping happened to be there before me with thier huge cart and then it happened*** I fainted behind the cart and almost got run over by it had my RN would of not found me and started to hear ringing in my ears and blurred yellow vision and severe right side cramping and I could not stand on my own or get up from the floor and I was crying in excruciating pain. I felt like a failure unable to have children and was quite embarressed that my workplace knew what was going on since the ambulance was performing my vital signs right in front of them. And then my RN has the nerve to say "we didn't even know she was pregnant" like I mean this is personal and I had a feeling I was miscarring deep down but was hopeful I would be wrong and did not want to tell people until 3 months had passed cause then chances were high that the pregnancy was fine according to books at 3 months and who reveals they are pregnant that early anyways? I personally never heard anyone reveal that until 2 months have past at least. Not to judge anybody by the way, but I think this way because I feel that incase you have an unsucessful pregnancy you can hide it or at least try to and not have to deal with all the questions or comments since it's not so easy to talk about and it's not like your talking about about having a cold or a stomache flu. Unless your open like that. In this circumstance it's different and beautiful to reach out to each other for help/advice/comments since your really asking for it on this website... Next my doctor sends me for lab work and tells me that it is possible that I have  tubal pregnancy since when he physically pressed on my abdomen to see how many weeks I was and he said that I wasen't pregnant. Well I took 4 home tests and 2 doctor office exams that confirmed I was and he knew that. And at 6 weeks doctors should feel something in a physical exam. So I had to wait one whole week before I had laparoscopy surgery to remove the fetus since the reason I fainted was because it was growing way too fast and that is unnormal and I was at high risk to die. Full recovery took me almost 2 months and I was hosptalized 3 days and heavily medicated. It was very difficult to go back to work and have to put on my best poker face along with all the staff's questions and rumors and gossip. But who cares about that right? sometimes woman worry about stupidities such as that when I should have only worried about whether I was gonna live or die or be able to have children again. But I didn't give up sometimes it's just one of those things that happens in life and we are very lucky nowadays compared to 100 years ago with all the tecknology that has come along. Just imagine back then that when woman had tubal pregnancys and left it undected they for sure passed away. Just keep your head up and I wish the best of luck to you and your next time to get pregnant may be the charm.  I was sucessful to have a healthy 7 pound boy 2 years later. And I've prepared myself this time to not get excited about this pregnancy just in case something goes wrong since your at high risk to have another tubal pregnancy after you've already had one and I choose to wait my 3 months with hopes that I'll go on to deliver a healthy baby before I reveal to family and friends. Only my husbend and mother and whoever reads this post knows that I'm pregnant. And I am spotting red but not all the time with very mild discomfort and have sore breasts for symtoms. But I will go and see my doctor tomorrow for the first time since I've learned I'm pregnant. Please take care of yourself and I wish you the best of luck!
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Avatar universal
Thank you everyone for your kind words, and making me realize that I am not alone with this. ((HUGS)) to all of you that have lost, and the experiences you have endured to get where you are now.
Yesterday was extremely hard on me, after two weeks of cramping, diarrhea, hot/cold flashes, I went to the bathroom and heard a sploosh! sound. When I turned around (thank goodness there wasn't diarrhea at that time), I noticed a clear oblong object, about the size of a twonie (or roughly 2 inches) with a tail on it that was red. I am not sure if it was the empty sac (as my tubal grew from 2.8 cm to 5.8 cm) or not, but at that point I came to terms with what has been happening.
Other thank that, they sent me home from my last ultrasound (which is a good sign I guess) and hopefully will be back at work soon.
Once again, thank you for helping me thru this. It means the world to one that feels like she lost hers.
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Avatar universal
Hi everyone, I'm new and don't know many of the abbreviations so bare with me. I conceived my first daughter via 2nd IVF. I had one period after stopping breastfeeding. As I was approaching 2 months since that period I was going to call the Dr. to be seen and get priveria meds or whatever I needed to get myself back on track. To my surprise and shock I was pregnant. After just a few days, and a Dr. appt. wherein I was told everything was ok, I didn't feel right Friday. I was trying to tell myself it was just my mind and worry since we conceived naturally this time around...I was sure something had to be wrong. Well after hours in the hospital Friday I was told that I had a presumed ectopic pregnancy. This rollercoaster was too much! My choices were the D & C or Methotrexate. I decided on the shot since I wanted nothing more than to see my daughter. Today is Sunday morning and although today my cramps are slightly more intense I have not yet started to bleed.  How long does this process take??? I just want this to be over with! Any help would be greatly appreciated. I have very few women in my family to discuss this with and appreciate any guidance. The sense of loss is really setting in and after reading some of your posts, I am scared to see what's to come oer the next few days. My Dr. told me that only 5% of the time a 2nd shot is necessary. This doesn't seem to be the case in what I have read. I am currently working and dreading the week ahead. My boss is already not very understanding since I've been back after having my daughter who is 8 months old now.  Again, any guidance would be appreciated.
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Avatar universal
I just had to have a DandC when they didnt find any fetal tissue they knew it was ectopic..I had one shot of the methotextrate..On Wednesday. I spotted a little and now today on Monday I seem to have dropped my Sac and have had some heavier bleeding. The cramps are pretty unbearable I think they dont tell you how bad it can really be. Well Thank you for listening and to all who have lost keep looking ahead and keep trying.....Someone told me even though it didnt work this time at least I know I can get pregnant so why give up...
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Avatar universal
i just went through the same thing 2wks ago. i am just now starting a normal mens. you are having the same symptoms that i had. slight cramps light bleeding. some dizziness.
have you been really tired too. so far it sounds like everything is running like normal. you have my deepest apologizes for your loss i know what you are feeling.

best of luck.
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Avatar universal
I have just recieved my methotrex injection 3 days ago and I am experiencing cramping making it hard to walk, cough, (luckily I haven't had to sneeze) and move around quickly. I have not started to bleed and I'm not sure how long I should wait to before getting concerned. I have my follow up appt in 5 days, but I don't want to  wait too long if something is not right.
The question I have for all of you ladies is
How long did it take to start bleeding?
Were you cramping before that bleeding started and for how long?
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Avatar universal
HELLO EVERY ONE I AM NEW HERE AS WELL, ON MY 3RD ECTOPIC JUST HAD MY SECOND SHOT OF METHO ON THE 26TH IM HAVING MILD BLEEDING AND SOME CRAMPS HOWEVER AM NOW IN A SITUATION WHERE I HAVE NO INSURANCE AND HAVE NO DR TO FOLLOW UP WITH ON MY HCG LEVELS AS THIS IS MY MTHIRD TIME GOING THROUGHT THIS ITS NEVER THE SAME MY EXPERIENCE IN THAT PAST IS THAT MY BODY DOSNT TAKE TO WELL THE THE SHOT I HAVE ALREADY HAD MY TUBE RUPTURE ON THE FIRST OCTOPIC SO IM A BIT SCARED I GUESS IM JUST SEEKING ADVISE ON WHAT TO DO NOW
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Avatar universal
Hello ladies I too am having an ectopic and yesterday recieved my first metho injection. but what I was wondering is I am already bleeding, so how will I know when it starts to work? and what can I expect from this shot?
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Avatar universal
Hello all,
I just had my first metho shot on NYE.  This morning, around 4 am, I woke up in excruciating pain.  I tried walking it off but couldn't.  Trying to stand in a fully upright position was impossible.  The doctor's told me in the emergency room that I would have abdominal cramping, but never in a million years would I have imagined it to be so painful.  It was just as bad as the pain I was experiencing that brought me to the ER in the first place - but how does one judge when it's too serious to just sit at home?

My husband gave me two excedrin followed by two midol 30 minutes later.  After applying the heating pad, the pain started to dissipate after lying as motionless as possible.  I'm not sure if it was the pain that went away or the fact that I was just exhausted, but it felt like it had subsided.  

This morning, I was afraid to get out of bed and go through the pain yet again.  Once I finally did and used the bathroom, I noticed I was bleeding.  The doctor's never told me this would happen - in fact, they told me the baby would dissolve in my body but according to many posts here, it seems like it will be passed.  I'm even more mortified now knowing this.  Why would they lie to me?  And I was never told to not take prenatal pills, vitamins, or that I couldn't drink.  In fact, I wasn't even remotely clued in that I would be bleeding for weeks.

I guess I'm going through the right symptoms so far though.  I've been keeping pretty active, cleaning my house constantly, and just doing anything I can to keep my mind off what is happening.  When will this end?  
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Avatar universal
Hi all. I had a negative pregnancy test on the afternoon on Dec 5 and that evening had my period. 3 or 4 days after I had my period I experienced the sharpest cramps I'd ever felt in my life which lasted for about 15 min then subsided. I then noticed I started spotting. I have had period like bleeding for mostly the entire month of Dec. I finally saw my gyn on Dec 30 and she told me I was pregnant but should see an ob/gyn because she was concerned about the pregnancy. I went to the ER on Dec 31 because it seemed as though my bleeding was increasing. They did an ultrasound and took HCG levels which were 845. Turns out I also had a large cyst near my ovaries which I hoped was causing the bleeding and cramping. Unfortuneatly I had a follow up Dr visit on Jan 1 and my HCG levels only increased to 900 whereas they should have at least doubled within the 48 hrs. My Dr decided to give me the Methotraxate shot also on Jan 1. I was given two shots both in the hip which was pretty painful. I am still having the same symptoms today that I had prior to taking the shot. I'm still bleeding and cramping is probably worse than before. I go to the Dr tomorrow for have the HCG levels tested again but at this point I;m getting frustrated because I've lost my baby, I've been bleeding for a month, and the pain does not seem to be improving.
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Avatar universal
Hi Emil

I went to my doctor today for the first time since getting my shot on the 31st for bloodwork.  Unfortunately, the pain will continue for a bit until your hormone levels are at zero but the good news it, they should become less and less within time.
I asked for tylenol with codeine because the pain has been tremendous at times.  It sometimes got to the point that I couldn't stand or walk or think straight.

If you feel faint, nauseous or the pains become stabbing, you should call your practitioner immediately.  It's frustrating because it seems they don't offer enough information for a woman to feel secure about what is taking place.  The worst part for me is feeling my baby is still inside me, slowly dying, and there's nothing I can do about it.  It breaks my heart more and more each day.

I'm sorry you are going through this, too.  Bring a list of questions for your doctor.  I went prepared so that I didn't forget anything when my emotions got the best of me.  Good luck to you!

Kat
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Avatar universal
I had a ruptured ectopic pregnancy on 11/19/08 and almost die because of the loss of blood.  Prior to the ruptured, I didn't have any unusual signs or symptoms.  What sad was that I found out I was pregnant 2 weeks prior to the ruptured.  When I call to make my 1st doc's appt, I was about 4 weeks along.  The nurse went through the routine questions and told me that no appts were avail until December 15th (at 12 weeks pregnant).  The nurse informed me that doctors don't see patients until they are between 8-10 weeks along but since no appt is avail, the doc can't see me until my 12th week.  It was my first pregnancy EVER as I just got married in September.  On 11/19, while in excruciating pain and feeling fainted, I called the doc's office and was told that the doc can't see me but the nurse will call me back to see if I need to do something.  The nurse then called and told me to go to the lab and have a blood test along with an ultrasound done.  However, no appt can be made so I will just have to wait for my turn.  I informed her that I couldn't drive due to the pain but I will call and have my husband take me in a couple hours.  I called my husband but was so tired, I could barely talk.  Luckily, my husband came home right away because by that time, I was in and out of conscious.  At the ER, they didn't think it was that serious until my blood pressure dropped down to about 30.  That's when they called the doctor (my doctor, the busy one that I couldn't see).  She performed an emergency operation on me known as a laparoscopy surgery.  Six weeks after the surgery, my HCG level was still at 2700.  She gave me a methotrexane shot on Dec 15th.  Today is Jan 10th and my HCG is at 21.

My question now is that my doctor refused to give me a post-methotrexane lab work to test for the liver and kidney as the methotrexane could cause of some damages to them.  She said she does not do that unless you have a history of liver or kidney's problem.  I don't know what the signs and symptoms of liver and/or kidney's problem are so how would like able to tell whether or not I should be worried?  It has been almost 2 months after the ruptured ectopic pregnancy and I still have some slight pain my stomach especially after a long day of sitting at work and after eating meals.  Lately, I have been having problems with my bowel movements.  Either I can't go or when I do, it's often in a form of diarrhea.  I also have probelms sleeping at night.  Is there something wrong with me?  I'm 30 years old and in good health.  I'm sure why I have so much problems with the pregnancy.  By the way, I had a blood transfusion on Nov 19th, after the laparoscopy surgery.  The doctor said that I lost about 30% of my body's blood.  Without the transfusion, my organs may not survive.  She wanted to give me 4 bags but I opted for 2.

Thank you in advance for any help or comments from any of you
.
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Avatar universal
I have had 2 ectopic pregnancies. One 5 years ago My second on 1/29/2009. For my first I had a laparacospic surgery. But with the scond I had the methrotexate shot. I do not know what to expect I was given the shot on 1/29/09 I have been bleeding since 1/15/09 I still have pain and my doctor said is normal. I have my doubts. I feel nauses, I have diarrhea and sometimes vomit. How long does it take for all this to go away? A couple a days later after having the shot I went to the washroom and notice that something came out but it happenned more than once it hapened about 5 times.  Help I need more info. Thankyou
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Avatar universal
Hello everyone,
You don't know how helpful it is to read the experiences of other women who have gone through the same thing as I. I found out I was pregnant while on a trip abroad, I came back to the US and tried getting an appt with my Ob/gyn because of my past history trying to get pregnant and my partially blocked left tube, plus I was recommended for IVF cause I was 32 years old, and not pregnant, even though trying for 3 years.  I was so happy to find out I was finally pregnant, and couldn't wait to have a sonogram to see the baby. I got back to NY and my doctor could not see me until the 8th week of pregnancy ( I guess she figured if it wasn't viable I would just miscarriage.) Well, I was alredy in the 5th week, and feeling like a doctor needed to see me. So I got a new doctor, and she saw me at the 6th week. That's when my doctor found out that my beta HcG level was way too low for that stage of my pregnancy, and explained that one reason could be ectopic. So the sonogram confirmed that there was no fetus where it was supposed to be, but rather in the corner of my uterus.  So my doctor gave me right away a Metho shot, systemic, which was just awful. I got diarrhea, nausea, I could not function and took off from work. 4 days later I got see the sonographer again, and found out that the baby was still alive, there was a fetal heart beat, and I was scared as hell.  So I was given a localized shot right in the uterus of Metho,  This was so painful, I was hospitalized, just for observation because the doctors were afraid it would burst and cause hemorrhaging. I was fine, but my HCG was still 39,000. So since then I have been getting blood work and a sonogram about 2x a week, and the doctors say that everything is going as planned. Today I went to the doctor and the sonogram showed a lot of blood, I could tell the sonographer getting very nervous, but she didn't say anything, running to the doctor to tell him what she saw. The doctor appeared calmed when I met with him, and told me that the linning of the uterus would be coming out, but my dear lord, I never thought I would see what I saw come out of my body just a few hours ago, about 10 days from my second metho shot. The first blood clot was round, and seemed like the fetal sac (i could not see any baby inside), but it was just big and about 3 inches in diameter. A few seconds before it passed I had nausea and I was salivating like crazy, I spit out half a small cup of saliva, which was salty and just watery, not it slimey.I had the most severe cramps just before it happened. I took 3 advils, and had my husband heat up a towel so that I could place it on my belly. That helpef for a few minutes, bu tthe cramping continued, so I went into the tub full of hot water.  That helped but i still had the most excrutiating pain I have ever had. It felt like the pain of 4 periods put together. After my first blood clot passing, I went to lie down on the bed. I stood there for about an hour, and then I had another set of cramps, and I went to the toilet, and right before I sat down, I passed another blood clot. This one was long, about 6 inches, and one side was red like liver meat, the other side was whitish/clear like the insides of the stomach lining. It was so gross, I called my husband to look at it, he was grossed out, but I felt it was imporant for him to see.  
So now I am sitting here and I feel so much better. No more cramps, for now, I hope they stop. It feels like the cycle has been completed, and my uterus feels cleaner and fresher, and I feel like this experience is over.
Well, I feel like my doctors have been wonderful, except for my ob/gyn not been honest about me passing the blood. She specifically said that I would not see a period or blood for 2 months, that my body would just absorb this, which was not true, but now I understand that they possibly say this to you to prevent you from getting scared paranoid about th ewhole experience.
One thing I want to recommend is alternative treatment, such as aromatherapy massage oils. I took a year-long course in aromatherapy, and I decided to make a blend with essential  oils that have abortificent qualities (basil, marjoram, jasmine) and I really feel like massaging the oil on my belly helped.
I hope that all you guys going through this experience work closely with your doctor, and I hope you have good doctors that care about your well-being. Follow-up is so imporant.  Above all, stay positive and trust your inner instincts. My doctor wanted to give me another Metho shot today, and I refused, opting to wait.  
Please heal quickly and pray to whomever you believe in to help you get through this experience.
Warm regards,
NYC Conural Pregnancy
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Avatar universal
Hi Everyone,

I got an ectopic pregnancy from my 3rd round of IVF (each time we only get one viable embryo, none to freeze).

My bHCG to test whether the IVF was working or not was 15. They told me "I'm sorry it hasn't worked, but looked like it tried to implant, it's our best result yet" I already knew it hadn't worked as I had my period two days before the test, it lasted a week and was the heaviest I'd ever had.

I had to repeat the test a week later to ensure bHCG had returned to 0. However this test came back at 550, a big rise over 7 days. They requested I book in for an ultra-sound the following Monday which would put me at 6 weeks, and advised it was either an intra-uterine pregancy or ectopic. I thought I might be pregnant with a little trooper that had hung on through my period and was just a bit slow to start. My hopes were rising... This was Monday.

Tuesday I rang them to say I had started bleeding again (period finished Sunday). This was different blood - very thin and very bright red and runny. They said, ok come in for a blood test tomorrow (Wednesday).

Wednesday's result: 605, a rise of 100 since Monday. "Have you got any pain they ask?" Now that you mention it, yes, a dull ache in my right side and a lot of cramping. "Can you come in for an ultra-sound right now?" Yes, I can, I'm now freaking out majorly.

Ultrasound confirms 2.5 cm mass in my right fallopian tube. Devastated! Frightened! I was offered laparoscopy to remove the tube (they wouldn't remove the mass from the tube as they believe the risk of scar tissue and repeat ectopic to be too high) or methotrexate.

So I opted for the methotrexate - only warned of mild symptoms such as nausea, mouth ulcers, diarrhoea. I barely got those after the first shot. This was still Wednesday. (bHCG 605)

Next blood test for Monday March 2: bHCG now 1617. How much has it risen?!! Why isn't it working??!! Was told not unusual for a small rise after the injection... Next blood test & possible second metho shot scheduled for Friday.

Tuesday I can't stand it anymore - I ring and ask for another test to be done on Wednesday - my reasoning is that the pain is worsening and if the metho is working my bHCG should have plateaued or dropped by Wednesday, 7 days after the shot. Otherwise if it's still rising, I need the tube out asap, before I rupture in my sleep.

Wednesday bHCG: 1495 - it's dropped just over 100. Panic abating slightly....
Friday bHCG: 1332 - no-where near enough to get 15% below the base level of 605, so another shot of metho.

Sunday night cramping like you wouldn't believe! (well you girls all probably would) I curled up into a ball and lay on the couch moaning.

It's now Tuesday March 10, 2 days later and it still hurts to walk and my ovaries are throbbing, my whole abdomen hurts, stabbing pains in my bottom. The bleeding is worse and frightening - I sit on the loo and it just drips, every 5 seconds. Some large clots are starting to appear.

I have a theory that the metho didn't work so well first time around because I was taking high dose folate - 1000mg folic acid per day, (IVF reccommendation) and had taken some the day of the first shot (when I was oblivious to the ectopic). Maybe it neutralised a lot of the first dose. They should take this into account when they calculate the dosage of the metho.

So I'm booked in for my 3rd shot this Friday (March 13) but I really really hope I don't need it, especially since the side effects seem to be cumulative.

Bye for now.
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Avatar universal
It is so nice to read these stories to know I am not alone.  Others just don't get it!

2/20 I went in for my 5 week sono (after successful IUI) and they saw nothing, I came home from the Dr and I was cramping so bad - they rushed me to a radiologist - saw nothing.  5 sono's on one weekend & nada!  that Wed I had 2 shots of methotrexate.  Felt totally fine for 2 weeks.  Yesterday after my 2 week blood work (levels went down from 1200-450) I was never in so much pain in my entire life!  8 hours straight if massive pain. 3 Tylenol and a heating pad finally put me to sleep.

They don't tell you the cramping would be that bad!  Also, i've been bleeding for 2.5 weeks.  I feel like there should be one big gush (sorry..) is this what I am waiting for?  

Any advice would be great!
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