Two studies have found an increased risk of miscarriage with the use of NSAIDs such as ibuprofen (Motrin) early in pregnancy; however, several other studies did not find this association. There are also concerns that drugs such as ibuprofen may interfere with implantation of the early fetus. While a clear risk has not been established, women who are
trying to conceive may wish to avoid ibuprofen.
When ibuprofen is used as directed in the first and second trimester of pregnancy, it is not associated with an increased risk for birth defects. However, ibuprofen is generally
not the pain reliever of choice during pregnancy because there are concerns with the use of ibuprofen during the third trimester.
As with any medication in pregnancy, it should only be taken as needed and with the approval of your health care provider.
There is concern with the use of ibuprofen in the third trimester. The greatest concern is for premature closure of the ductus arteriosus (a vessel in the fetal heart), which
can lead to high blood pressure in the fetal lungs (pulmonary hypertension). The use of ibuprofen later in pregnancy may inhibit labor or cause reduced amount of amniotic fluid
(oligohydramnios). Therefore, it is recommended that women use ibuprofen only under a health care provider
have you checked safefetus.com? Motrin is category D if used in the 3rd trimester. Check the site out for more info on fetal risk and brestfeeding.