I have to take three Benadryl, which is whats in tylenol PM, but I still sleep restless. The best for me is the Unisom. (or the generic one!) It is the same ingrediant that is in Nyquil, minus the alcohol. That works so much better for me. If you have a week to sleep, I strongly suggest that you just keep taking them so you sleep right through it. I'm on day 2 CT, and last night, I slept until 3:30, and then took more sleep aid and slept until 7:45! I woke up feeling like sh*t, but I plan on taking more through out the day, and just sleeping, nothing but sleeping. They are not addicting, and the pharmist said it was a great idea! God dang they knock me OUT! So far, Ive just slept right through all this. It also takes all of the restless RLS feeling away when it starts to kick in, and the crawling skin. Then, I just knock out fast! Hope this helps someone! It just works so much better than benadryl, or anything "PM".