it will affect your organs immediatly, but it wont damage them.ive seen 80 lb crack users run 2 miles thru the city to elude police, so i dont think its gonna be the organs that kill them.its usually a blown heart , or a stroke.... ru diong a research paper
i am 5'6" and lost from 120 to 85 lbs and all my organs were still functioning...i dont know how well lol
UMMM i would like to say it effects all organs as soon as it gets in your blood......
but again this is something that varies from person to person. What happens to you may or may not happen to me.