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Another question for Ryan
by ccamrine, Jul 29, 2007 10:48AM
I'm wondering why after about eight years of taking antidepressants off and on, and I seemed to do fine, why they suddenly stopped working and made me even worse. I was on paxil for three years , it was working just fine and then it just stopped working. I started feeling woozy, like withdrawl, and then my panic attacks came back full force. Then everything they tried on me since that time, effexor, lexapro, cymbalta, prozac and zoloft just made me worse. Why do you think that happened? Could hormones have played a role in this?
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Paxil is less stimulating than the other SSRI's, which is probably why you had a negative response to Effexor-XR, Lexapro, Cymbalta, Prozac, and Zoloft, all of which respond more favorably to depression.
Switching to another drug class will often re-establish effectiveness. The Tricyclics (Elavil, Sinequan), the Tetracyclics (Remeron, Trazodone), or the Benzodiazepines (Klonopin, Librium, Valium) are all options. Klonopin has the greatest advantage if the primary component is anxiety.
There is little doubt that a hormone imbalance could've played a role as well.
Ryan