Three years ago I switched from Celexa to Zoloft. I know that you are doing the exact opposite, but I did not feel too much of a difference, however, Zoloft seemed to work a little better for me. We are all different and different medications work differently on each individual. I felt a little anxious while I was doing it, but I am not sure if that was from my personal feelings versus the medication. As long as you are in constant communication with your doctors and counselors, you should be fine:)