Duloxetine withdrawl?

[Suz245]

Has anyone had bad physical symptoms coming off duloxetine i stopped them a week ago cutting down to 1 a day for a week then my doctor said just start new meds ( fluoxetine) the next day...

I can hardly stand up i am so weak shakey.. Muscle spasms generally feel so unwell pain and co ordination problems...

Can someone please tell me this will stop ?!!

[g2pankhursts]

Every body is different and unfortunately these effects should only last up to 3 months max, if your still experiencing problems, you may have to go back onto a small dose of duloxetine again. I always recommend being on duloxetine for 12 solid months at finding the correct dose for you

[g2pankhursts]

Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed. This is why duloxetine should be withdrawn extremely slowly and only under professional help