One more thing- anyone on Zoloft- I have been on Zoloft 100mg/day for about 2 years, again with few results. I note from the on line info that dosages of up to 200 mg/day are OK- needless to say I should explore having my dosage raised before switching from Zoloft to something else? Also, anybody have any relief from OTC stuff like St. John's Wart, Magnessium supplements, Serydyn or others, or are these a waste of money? Finally, as an alternative to Xanax, does Klonopin work as well as Xanax, but not as addicting and not making you "loopy" or visibly impaired, to prevent panic attacks and at onset of symptoms to ease one? Thanks again, Johnstown!!