I have been on SSRI's for about four years. I switched from Paxil to Lexapro 20 mg about a year ago. About two months ago, I reduced this to 10 MG and added Wellbutrin at the advice of my doctor, because I wanted to see if it would increase my ailing libido. First it was 150 MG SR twice a day, then to 300 MG XL. Nine days ago I started a new generic at a new pharmacy and the pill was enormous. Foolishly, for the next six days I broke the pill in half and took both halves in one sitting (with my 10 mg lexapro at the same time.) I had terrible anxiety, nasuea, headache, heart palpitations, and felt awful in general. It wasnt until two days ago that I called my doctor and she said to stop cutting the XL in half immediately. The next day I took a Wellbutrin 150 MG SR pill I had left over, and I had a similar reaction. I have been cold turkey for two days.
For all of the days that I was cutting the 300 MG in half, I had NO erections and was unable to obtain one. I think I read that too much seratonin can kill your sexual function. Now two days after the drug has (presumably) left my system, I STILL cannot feel any sexual sensations whatsoever. I have no sex drive and my penis is so small and soft that I cant even feel it. Did i do serious damage? If not, how long until I should feel normal again after quitting the wellbutrin? I am scared that I fried my brain by essentially overdosing.
The dosages of medication you were taking could not cause any long term damage to your brain or other organs. When you were cutting the extended release medication in half you were getting a big dose all at once, but this would not cause any long term problems with this medication. You may be experiencing serotonin withdrawal symptoms. Antidepressants should not be stopped abruptly without consulting your physician. In most cases the doctor with prescribe a lower dosage so that you can gradually wean off of the medication. The withdrawal symptoms usually last one to two weeks.
Lack of sex drive or temporary impotence is an unfortunate side effect of antidepressant medications. If your depression is mild, positive lifestyle changes and psycotherapy may help you overcome the depression and regain your sex drive.
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