You know, I mostly only take ib profen, which is what makes aspirin for headaches and other pain and I've taken powerful kinds for the horrible migranes I used to have. Do you know when I started having my worst episodes started after taking those powerful medicines. I had my melt down at work while I was taking them, in fact, in 2008. So maybe it would work for some people, but I don't think they would help me. I think it is just like all of the other medicines. It will work for some but not for all.