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AFP score?

Should I be worried that my AFP is 9.8. I have hepc and fibroscan in stage 3?
Best Answer
446474 tn?1446347682
COMMUNITY LEADER
No you should not be concerned. Your AFP level is within or close to the normal range, depending upon your lab where the test was done. Typical ranges are from 0-8 or 0-10 ng/ml. When it is said that a high AFP level may indicate development of HCC the AFP level will typically rise higher and higher over time into the hundreds of ng/ml as the cancer grows. So a "high level of AFP" caused by HCC means an AFP level many times the normal range not a few points above its normal range.

Also while AFP can rise because of HCC, it can also be elevated in persons infected with hepatitis C because inflammation of the liver can also cause higher than normal AFP levels. It is not uncommon for people with chronic hepatitis C to have higher than normal AFP levels. This is one of the reasons that AFP is never used alone to diagnose HCC. AFP should always be combined with an imaging study for proper surveillance of HCC (liver cancer). Note that 40% of HCCs (almost half!) don't produce the AFP tumor marker so they would be missed without imaging. Also imaging (typically CT or MRI) is how typically HCC is diagnosed. It is only with imaging that the characteristics of HCC can be differentiated from other usually benign lesions in the liver.

Also note that the increase risk of HCC is small in those who don't have cirrhosis, stage 4 liver disease where the risk is much higher.

Of course the best way to avoid developing HCC in anyone currently infected with hepatitis C infection is to be treated and cured. After being cured of the virus (which now can occur in only a few months) greatly reduces the risk of the development of HCC post SVR, it also prevents the development cirrhosis and it complications and leads to a more healthy future life in general as well.

Get treated and cured so you never have to risk developing HCC and its life-changing consequences.

Be well.
Hector
Liver transplant recipient due to HCC.
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446474 tn?1446347682
COMMUNITY LEADER
Nausea and dizziness are not symptoms of HE.
I would call your doctor and get an appointment to get it checked out.
Make sure you don't have a temperature. It could be a flu or infection.

Good luck to you.
Hector
Helpful - 0
Avatar universal
I couldn't quite pinpoint the spaciness on Sunday but today it feels like the room wants to start spinning. Nauseous and dizzy
Helpful - 0
446474 tn?1446347682
COMMUNITY LEADER
Regarding feeling spacey can you explain further how you are feeling?
HE has very particular symptoms so if you could describe what you are experiencing that would be helpful. HE symptoms are not usually associated around having a meal as the toxins which are created during the breakdown of digestion in the intestine many hours after eating.

Keep in mind that Only people with advanced cirrhosis can have HE. HE is a complication only happens when a person has cirrhosis plus portal hypertension. Meaning you would have to have an enlarged spleen and changes to the blood system around the liver as well as a cirrhotic liver. All of these things would all show up on any scan report and a cirrhotic liver and enlarged spleen are easily detected with an abdominal physical exam . Also it would be typical to have some degree of varices which again would show up upon an exam where cirrhosis was suspected. (Endoscopy/Colonoscopy).

Take care.
Hector
Helpful - 0
Avatar universal
By the way. I've read your story from another post and I'd have to say your story is quite moving. You had me in tears.   Keep up the awesome work.  I'm glad your here
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Avatar universal
Thank you HectorSF. I am just waiting to see my liver specialist. Taken all the necessary test. My follow up appointment is August 18th.  I hope they can get me in sooner though.  I've been feeling spacey after my meals recently and today's the worse. Not sure if it's the HE I been reading about.  If it gets worse I feel I should go to ER..do you agree? This is all new to me..
Helpful - 0
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