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genetic thick dry skin on hands and feet

My fiance has very thick dry skin on the palms of his hands and the bottoms of his feet; it's like the whole palm or sole is callussed. I know it's genetic, almost everyone on that side of the family have it. What is it?
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Avatar universal
Does anyone have this and know exactly what genetic mutation you have? I have this and am waiting to hear if I have PTEN mutation. Anyone ?
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I too have the same genetics.. Hands and feet both have calluses. And I have managed to pass it on to my son. I would never change that even if I could. The hands and feet that I have given him are a super power. I have never had blisters on my hands and feet, pushing how far I can go... From walking across hot coals, to having my hand cut open by a barbed wire fence which also healed in 3 days. Though the downside is the bullying from kids that just don't understand,because it's different. But to show them the things that are possible is what really makes them envy what we have. For the fact that I can look at my hands and notice no scars after the many different times of burning, scraping,and even having them cut open to a point where normal people hands would need stitches but I simply folded the skin back over and it healed. That's what makes us awesome!! To pass this blessing in disguise is truly incredible!!!! And any one that reads this if you have frytag blood in you or just someone to talk to reply and I will message you!!
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I have had this issue my entire life. Inherited from my dad. I take a long bath like an hour then immediately use a very rough grit sandpaper disk and scrub off the thick skin. If I stay on top of I and do weekly i have almost normal soft pink feet.

If i don't remove the skin for a month or two it will crack and bleed.

The ped egg is good for toes but I use a drywall rasp for the bottoms.
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Avatar universal
I was born with this genetic condition. On both my hands and feet. I grew up HATING it. My great Aunt has it, then I, my mothers first born child/daughter born with it as well as my first born child/daughter was born with it on her hands and feet. My mother took me to a dermatologist when I was 6 or 7, and they said they have never seen anything like it, and that there's no cream nor surgery that would cure it, if they removed it, the skin would just grow back thick, dry, and callused. I've learned over the years, best thing you can do is maintain it, soak you feet a few night a week in warm water with coconut cream or oil, for 30mins to an hour, dry them, use a pumus stone or foot file on them, and use coconut cream or goldbon lotion on them, put on cotton socks to keep the moisture in over night. As for the hands I like using Nivea hand cream, its non expensive, it comes in a dark blue tin or round lotion jar. It's makes my hands sooo soft and the dryness of my hands absorb the stuff, unlike most lotions out there, it works so good :) I used to always say I was cursed with these hands, but IDC anymore, it's who I am. And be careful when u smack someone BC these hands will hurt someone more than intended lol...:/ just try your hardest to keep up on them, if you go months without keeping up in them, they Will get BAD....
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Avatar universal
Hey!  Has the lanolin cream been working well for him?  I'm considering of investing in some!  Hope to hear from you soon....
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Avatar universal
I have excess skin development that appears as thicke layers of calluses on both palms of my hands and soles of my feet. The condition is called Palmo-plantar keratoderma.  It is caused by a genetic mutation of the keratin gene that is responsible for skin cell production.  I have tried Vaseline which can be great only for cracks.  Other than that it dries the hell out of my hands.  I always moisturize my feet with Vaseline and wear 100% cotton socks and rarely wear sandals.  The recent struggles have been my hands.  I work on a computer all day and it has progressed quickly.  Cocoa butter works best over urea cream based and every other product I tried out there which includes Glycerin/O'Keefe for construction hands/Topical Cortisteriods/5% glycolic acid with Vaseline/Coconut Oil/Olive Oil and even prayers etc. Of course it never helps living in a dry climate place. I will be looking soon into Lanolin cream and see that works.  To avoid the debilitating issue, I use a nail clipper and stay on top of the layering.  So far so good! As for the feet I let it buildup and then visit the podiatrist who peels it off like a potato! I don't have kids but my dermatologist informed me there is 50% chance of passing it down if both parents have it.  As per my family history I am the only blessed one to have this.  It concerns me as I am only 25 and super ambitious and knowing my career might be an obstacle when this becomes a bigger issue.  If anyone has tips on how to manage it that would be lovely.  I've done my share :)
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