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Heart Disease  (Expert Forum)
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Another PVC Incident
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Another PVC Incident

by Twinsplusone40, Jul 20, 2003 12:00AM
My husband was taking Prednisone and Benadryl for a particularly nasty case of Poison Ivy.  He was on the short burst of Prednisone that taperd down over a week period.  He was taking 50 mg of Benadryl at a time along with the steriod.  About 4 days into this, he developed palpitations and a feeling of his heart pounding.  Since he has never had this before, we went to the ER.  He had an EKG, blood work and a chest x-ray.  Everything was entirely normal.  They mentioned that both drugs could cause this.  My question is this, after two weeks, he is still getting small bouts of palpitations. Are the palpitations as a result of the drugs or just a coincidence?  He DID drink large amounts of caffeinie in the form of soda, which he has cut way down. Does it take awhile for things to settle down after an incident like this?  He does not smoke, nor drink, but could use to exercise more. Thanks for your help.

by CCF-M.D.-RCJ, Jul 20, 2003 12:00AM
Twinsplusone40,

Thanks for the post.

You mentioned PVCs in the title, but no where else.  I'll assume that the ER physician or nurse stated that your husband had these on the monitor ...

I have not heard of low dose steroids leading to PVCs.  High-dose steroids, such as that used for cancer or lupus, can lead to palpitations, so  I suppose that some people might experience increased PVC/palpitations with steroids.  The good news is that these should go away when the effects of the steroids wears off -- maybe 1 to 2 weeks.

I can't say that either one of these drugs is causing the palpitations, other changes in his lifestyle could be the culprit -- including lack of sleep from itching!

Hope that helps.
Member Comments (2)

by medking, Jul 20, 2003 12:00AM
I had exactly that issue as described. Benadryl is a no no for anyone who has some suceptibility to tachycardia, PVC's or any other irregularities of rythum. It was absolute hell for me when I took this for a rash. Always ask before taking any meds.
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